TERAZOSIN HYDROCHLORIDE

Alpha Blocker

Brand names: Terazosin

Pregnancy: Category COral

Mechanism of Action

Pharmacodynamics A. Benign Prostatic Hyperplasia (BPH) The symptoms associated with BPH are related to bladder outlet obstruction, which is comprised of two underlying components: a static component and a dynamic component. The static component is a consequence of an increase in prostate size. Over time, the prostate will continue to enlarge. However, clinical studies have demonstrated that the size of the prostate does not correlate with the severity of BPH symptoms or the degree of urinary obs

Indications

INDICATIONS AND USAGE Terazosin capsules are indicated for the treatment of symptomatic benign prostatic hyperplasia (BPH). There is a rapid response

Contraindications

• CONTRAINDICATIONS Terazosin capsules are contraindicated in patients known to be hypersensitive to terazosin hydrochloride.

FDA Warnings

WARNINGS Syncope and “First-dose” Effect Terazosin capsules, like other alpha-adrenergic blocking agents, can cause marked lowering of blood pressure, especially postural hypotension, and syncope in association with the first dose or first few days of therapy
The risk of the events is greatest during the initial seven days of treatment, but continues at all time intervals
Because this condition can lead to permanent impotence if not promptly treated, patients must be advised about the seriousness of the condition (see PRECAUTIONS: Information for Patients )

Known Side Effects

8 documented side effects by frequency

Drug Not Working

1-10%

Fatigue

1-10%

Shortness of Breath

1-10%

Diarrhea

1-10%

Dizziness

1-10%

Weakness

1-10%

Falls

1-10%

Nausea

1-10%

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Compare With

6 available comparisons

Formulations

Dosage Forms

Tablet

Route

Oral