TETRACYCLINE HYDROCHLORIDE

Tetracycline Antibiotic

Brand names: Tetracycline Hydrochloride

Pregnancy: Category DOral

Mechanism of Action

Other agent

Indications

INDICATIONS AND USAGE To reduce the development of drug-resistant bacteria and maintain the effectiveness of tetracycline hydrochloride and other antibacterial drugs

they should be considered in selecting or modifying antibacterial therapy. In the absence of such data

Streptococcus pneumoniae

Mycoplasma pneumoniae (Eaton agent

and Klebsiella sp. ). Skin and soft tissue infections caused by Streptococcus pyogenes

Staphylococcus aureaus . (Tetracyclines are not the drugs of choice in the treatment of any type of staphylococcal infections.) Infections caused by rickettsia including Rocky Mountain spotted fever

Contraindications

• CONTRAINDICATIONS This drug is contraindicated in persons who have shown hypersensitivity to any of the tetracyclines.

FDA Warnings

WARNINGS Tooth Development The use of drugs of the tetracycline-class during tooth development (last half of pregnancy, infancy and childhood to the age of 8 years) may cause permanent discoloration of the teeth (yellow-gray-brown)
Tetracycline drugs should not be used in this age group, except for anthrax, unless other drugs are not likely to be effective or are contraindicated
Clostridium difficile Associated Diarrhea Clostridium difficile associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including tetracyclines, and may range in severity from mild diarrhea to fatal colitis
Women of childbearing age who are overweight or have a history of IH are at greater risk for developing tetracycline associated IH

Known Side Effects

10 documented side effects by frequency

Nausea

1-10%

Diarrhea

1-10%

Vomiting

1-10%

Headache

1-10%

Dizziness

1-10%

Weakness

1-10%

Joint Pain

1-10%

Fatigue

1-10%

Limb Pain

1-10%

Drug Not Working

1-10%

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Compare With

7 available comparisons

Formulations

Dosage Forms

Tablet

Route

Oral