VALACYCLOVIR

Antiviral (Herpes)

Brand names: Valacyclovir, Valtrex

Oral

12.1 Mechanism of Action Valacyclovir is an antiviral drug active against α-herpes viruses [see Microbiology (12.4) ].

papule

vesicle

papule

vesicle

Contraindications

• 4 CONTRAINDICATIONS Valacyclovir tablets are contraindicated in patients who have had a demonstrated clinically significant hypersensitivity reaction (e.g.
• anaphylaxis) to valacyclovir
• acyclovir
• or any component of the formulation [see Adverse Reactions (6.3) ]. Hypersensitivity to valacyclovir (e.g.
• anaphylaxis)

5 WARNINGS AND PRECAUTIONS Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS): Has occurred in patients with advanced HIV-1 disease and in allogenic bone marrow transplant and renal transplant patients receiving 8 grams per day of valacyclovir tablets in clinical trials
1 Thrombotic Thrombocytopenic Purpura/Hemolytic Uremic Syndrome (TTP/HUS) TTP/HUS, in some cases resulting in death, has occurred in patients with advanced HIV-1 disease and also in allogeneic bone marrow transplant and renal transplant recipients participating in clinical trials of valacyclovir tablets at doses of 8 grams per day

11 documented side effects by frequency

Fatigue

1-10%

Drug Not Working

1-10%

Nausea

1-10%

Diarrhea

1-10%

Headache

1-10%

Fever

1-10%

Rash

1-10%

Dizziness

1-10%

Shortness of Breath

0.1-1%

Vomiting

0.1-1%

Weakness

0.1-1%

No community discussions found for VALACYCLOVIR yet.

4 available comparisons

Dosage Forms

Tablet

Route

Oral