VANCOMYCIN

Glycopeptide / Oxazolidinone Antibiotic

Brand names: Vancomycin

Intravenous

12.1 Mechanism of Action Vancomycin is an antibacterial drug [see Microbiology (12.4) ] .

or those patients who cannot receive or who have failed to respond to other drugs

Enterococcus species and Corynebacterium species. For enterococcal endocarditis

use Vancomycin Injection in combination with an aminoglycoside. Methicillin-susceptible staphylococci in penicillin-allergic patients

or those patients who cannot receive or who have failed to respond to other drugs

Contraindications

• 4 CONTRAINDICATIONS Vancomycin Injection is contraindicated in patients with known hypersensitivity to vancomycin. Hypersensitivity to vancomycin ( 4 )

5 WARNINGS AND PRECAUTIONS Infusion Reactions : Hypotension, including shock and cardiac arrest, wheezing, dyspnea, urticaria, muscular and chest pain and "red man syndrome" which manifests as pruritus and erythema that involves the face, neck and upper torso may occur with rapid intravenous administration
To reduce the risk of infusion reactions, administer Vancomycin Injection over a period of 60 minutes or greater and also prior to intravenous anesthetic agents
8 ) Phlebitis : To reduce the risk of local irritation and phlebitis administer Vancomycin Injection by a secure intravenous route of administration
9 ) Development of Drug-Resistant Bacteria : Prescribing Vancomycin Injection in the absence of a proven or strongly suspected bacterial infection is unlikely to provide benefit to the patient and increases the risk of the development of drug resistant bacteria

8 documented side effects by frequency

Drug Not Working

>10%

Fever

1-10%

Diarrhea

1-10%

Rash

0.1-1%

Low Blood Pressure

0.1-1%

Condition Worsened

0.1-1%

Shortness of Breath

0.1-1%

Nausea

0.1-1%

No community discussions found for VANCOMYCIN yet.

3 available comparisons

Dosage Forms

Tablet

Route

Intravenous