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Compare ABATACEPT (ORENCIA) and Baricitinib (Olumiant) — clinical data, side effects, and patient experiences.
ORENCIA · Other
How it works
12.1 Mechanism of Action Abatacept, a selective costimulation modulator, inhibits T-cell (T lymphocyte) activation by binding to CD80 and CD86, thereby blocking interaction with CD...
Approved for
Olumiant · JAK Inhibitor
How it works
Selective and reversible inhibitor of JAK1 and JAK2, modulating cytokine signalling involved in autoimmune inflammation.
Approved for
Estimated frequency (%) based on clinical trial data
Based on 18 Reddit discussions
ABATACEPT
0%
positive
10 threads
Baricitinib
38%
positive
8 threads
% of discussions mentioning each side effect
10 Reddit threads analysed for ABATACEPT
Overall Sentiment
Mixed
Comparison Threads
7
Avg Post Score
6 upvotes
Most discussed side effects in community
Threads directly comparing ABATACEPT to other medications
Two studies demonstrated that 2 biologic drugs decreaed COVID-19 deaths: [https://www.medspoke.co/taps/6540](https://www.medspoke.co/taps/6540?fbclid=IwAR0JQufrsac0UV_fKtyFbUfyyWRJBiTEBjYp1mMdzpFhfbEvszsaOniFOSg) Though this was a study on rheumatoid arthritis patients, I have many patients on bi
I was encouraged to post this even though it is not specific, practical information because people might find it hopeful. So here goes, but don't ask me for more info because this is all I know: I have had RA for about decades and Sjogren's for at least 12 years with significant symptoms. I have I
What on earth is the model for naming new drugs? They sound like kids pointed at a list of syllables and picked the ones that sounded worst together, or someone's using a bad Tolkein name generator. I assume they include references to component materials or something, given that many have common syl
Hi everyone! I want to know y’all’s experience with different Infusion treatments for RA vs injections. I am currently on methotrexate but it’s giving me pretty bad nausea and anxiety and am wanting to switch! My doctor diagnosed me with palindromic pheumatism with a. Positive RA factor. Any posit
Has anyone found the injections worked better than the infusion? Ive done 3 months of infusions and my team think it only appeared to work because i was on steroids. Ive now finished steroids and the pain in constant so we are going to try the weekly injections.
29, Female, white, 30w pregnant, 6', 240lb. Also have lupus & rheumatoid arthritis (dx 2016) and I'm in a flare up of my anemia of chronic disease. Gallbladder removed in 2013. Non smoker, lots of meds including plaquenil, abatacept, sertraline, welbutrin. No change in meds since start of pregna
I was recently admitted to the hospital for GI problems and they ended up making an incidental finding on my liver: "Within the posterior segment of the right hepatic lobe is a low-attenuation hepatic lesion which measures 2 cm (image 3:47). This could be a cavernous hemangioma but this cannot be c
Hello guys! I’ve been recommended to ask this in here so… I’d like to know about Rheumatoid Arthritis and Orencia Abatacept (medicine) in Canada The thing is, I’d like to someone very important to me (25F, 5”1, ~130lbs) can come to Canada and stay with me, but she needs this medication and haven’t f
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
8 Reddit threads analysed for Baricitinib
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
20 upvotes
Most discussed side effects in community
My father 60M developed symptoms of Covid-19 in Mid-April. On the tenth day of his symptoms, his saturation fell too much and we got him hospitalised (April 26th) he was shifted to the ICU 2 days later and he has remained there. He was first on NRBM up to 15L high flow oxygen, following which he wa
(For posting reasons: Age:35 / Male / Malta EU / 163cm 72.5kg / Non smoker for 3 years, started again 4 days ago) Hi all - I felt I need to talk to someone - I have posted numerous times about needed help regarding a left sided swelling and full body flushing. Some replied and some ignored and I und
What is you opinion on Baricitinib as COVID treatment in patients with bacterial co-infection (e.g. Sepsis from an alternative source) ? Should it still be contraindicated or is that acceptable as a short course?
Hi all - me again (35/Male/Europe/70kg) - sorry I post a lot - but I have no one to talk to regarding my situation. I'm supposedly the first in the world with this condition. My left side of my body seem to be slowly spreading an inflammation - which is pain full, and feel like it weakens your muscl
35 Male - with an un-diagnosed illness which is rapidly spreading. I have done MRI's, CT Scans, Bloods and Skin Biopsies. **Irregular Blood tests: C-Reactive protein Range 0-5** In February 2024 it was 2.1 / March 2024 it went up to 5 / April 2024 it is now 24.9. I am currently on Predisone 10mg -
• Age - 50 • Sex - F • Height - 178cm • Weight - 95kg • Race - caucasian • Duration of complaint - 11 months • Location - bloodwork • Any existing relevant medical issues (if any) - seronegative RA, eosinophilic esophagitis, possible pituitary tumor (non-functioning), central hypothyroidism, seconda
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
ABATACEPT is a Other, while Baricitinib belongs to the JAK Inhibitor class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles. ABATACEPT is administered via Intravenous or Subcutaneous, whereas Baricitinib uses Oral. Route of administration can affect onset of action and patient adherence.
ABATACEPT carries 4 FDA warnings. Baricitinib carries 1 FDA warning. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.