Medical Disclaimer: This site provides informational comparisons only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or pharmacist before making medication decisions.
Compare ATOMOXETINE (Atomoxetine) and GUANFACINE (Guanfacine) — clinical data, side effects, and patient experiences.
Atomoxetine, Strattera · Non-Stimulant ADHD
How it works
12.1 Mechanism of Action The precise mechanism by which atomoxetine produces its therapeutic effects in Attention-Deficit/Hyperactivity Disorder (ADHD) is unknown, but is thought t...
Approved for
Guanfacine, Intuniv, Tenex · Non-Stimulant ADHD
How it works
12.1 Mechanism of Action Guanfacine is a central alpha 2A -adrenergic receptor agonist. Guanfacine is not a central nervous system (CNS) stimulant. The mechanism of action of guanf...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 30 Reddit discussions
ATOMOXETINE
40%
positive
15 threads
GUANFACINE
47%
positive
15 threads
% of discussions mentioning each side effect
15 Reddit threads analysed for ATOMOXETINE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
587 upvotes
Most discussed side effects in community
For the first time in years I sat down, sorted through and cleared out all the old unread emails in my inbox. It took me about 2 hours and it felt great. Sorting through things that I know I should do but will leave for another time has always been a big problem for me so it was great to do that and
They snooped through my bag while I was visiting and found my atomoxetine. They obviously googled what it was. They think I’m just a lazy and irresponsible person and I should just stop and be a normal person and stop taking “unhealthy western meds” (I’m Asian). Honestly I don’t have the energy to e
* Since graduating 2.5 years ago, I’ve had 4 jobs as a frontend developer. * Every single time I’ve been fired, it’s the same reasons: delays, missed attention to detail, work needing multiple QA passes before it’s acceptable. * I joined my current company in December. In January, I started medicati
Phone call with a doctor a couple weeks ago. Literally broke down. "Sorry, we can't even consider the depression talk because you're on Atomoxetine." I cave in and ring my specialist, she has a history of shrugging me off but she actually walked me through the depression checklist, I show up as depr
I recently got diagnosed with ADHD. Doc gives me atomoxetine great. I can think before speaking. It's wild there's this pause before I blurt out what I'm about to angrily say. Eye contact feels less intense. There's no constant monitoring of yourself in environments. There's no constant thought cyc
I’m an Asian woman about to turn 30, recently diagnosed with ADHD. Growing up, I was called “lazy” and “irresponsible” because I was always late and procrastinated. My parents don’t believe in ADHD—they think I just lack discipline. Right now, I’m living with them, working part-time, and barely have
Yesterday my psychiatrist prescribed me a new medication for my ADHD, Atomoxetine. He told me it was hard to find, so I started my pharmacy run to see if I could find it. I managed to find a pharmacy that ordered it for me. After I payed for it the pharmacist commented that he had never heard of thi
I started strattera last Friday. It caused me to have intense dreams, except when I woke up I was stuck in the same state. It started two days ago, I woke up dizzy and confused. I accidentally ended up scraping my car on a large curb, but I believed it was from a lack of sleep. Yesterday, I felt ext
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
15 Reddit threads analysed for GUANFACINE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
751 upvotes
Most discussed side effects in community
Having ADHD fucking sucks. It’s not quirky, fun, or something that needs to become an entire personality. I’ve seen so many TikTok accounts that are all just “here’s 5 reasons you have ADHD” and then they base everything they discuss as mundane nonsense that doesn’t even pertain to ADHD. “You migh
Let me tell you a story. I’m a dad with ADHD, my oldest son has ADHD inattentive type, the middle son has ADHD hyperactive type, the baby is a baby, but we already have a sense she’s got something going on already. In the mornings, I serve up morning meds for everyone. A vyvanse for dad, fluoxetine
My son is profoundly autistic and very minimally speaking with a host of comorbidities, including ADHD combined type. We tried several stimulant formulations. He couldn't sleep. He became aggressive. He has used clonidine + guanfacine before bed to sleep. Today he started his second dose of clonidi
Decided three years ago to pursue a PhD in a discipline I love after finally took my ADHD seriously. Pursuing a doctorate was something I just didn't think I could do because of how my brain handles unstructured tasks (like writing a dissertation). Turns out with the right drugs (guanfacine + wellbu
I haven’t been able to sit down and read literally just a CHAPTER of a book in like 6 years. I crave just…. Sitting down and focusing on one task. Reading a book. Doing a puzzle. Cleaning my room. For reference I am diagnosed with adhd-c and on Sertraline and Guanfacine. I been on both for like?
I can’t believe nobody has ever recommended this drug to me before. I always struggled with stimulants as there would be days where I would have breakdowns or hyper focus on the wrong thing, couldn’t sleep.. etc. I’ve been taking guanfacine and bupropion for about a month and I REALLY NOTICE a diffe
Maybe it’s just me but I’ve gone through a gauntlet of medications (Adderall, Focalin XR, Ritalin, Metadate, Vyvanse, Dexedrine, Concerta, Wellbutrin, Strattera, Guanfacine) and each time I’ve ended up disappointed in them. At best, they give me a bit of energy/wakefulness and make it slightly easie
This is really long. I’m tired and frustrated, sorry. So I just got off my 11p-7a in the emergency department. We have this one doc, LC, who I’m pretty sure is out to get me. Does this sound dramatic? Yes. Do I actually think it’s true? I’ve been trying to convince myself I’m crazy, but I actually
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
Both ATOMOXETINE and GUANFACINE belong to the Non-Stimulant ADHD class. While they share a similar mechanism of action, differences in pharmacokinetics, dosing, and side effect profiles may make one more suitable than the other for individual patients.
ATOMOXETINE carries 4 FDA warnings. GUANFACINE carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.