BRODALUMAB vs CYCLOSPORINE

Earlier today I was browsing Reddit and stumbled [upon a post](http://www.reddit.com/r/AskReddit/comments/33ej71/disabled_people_of_reddit_what_is_something_we_do/cqkbwu7) It made me remember all I vowed to do if I ever managed rid myself of psoriasis. To this date I’ve not yet shared a whole lot

I'm currenlty engaged in a clinical trail for a new drug called "Brodalumab", am considering doing an AMA. Is there enough interest in this to warrant the AMA? My P had taken over 80-90% of my body and is now well under 5%. It has been a life changing experience and I want to tell others of the hope

Hello folks, Apologies if this is against the rules despite my reading them, I wanted to ask if folks have any experience with Leflunomide with treating psoriatic arthritis. I'm already on Brodalumab which has completely reversed the skin side but now at 35/36 I've started getting awful joint pains

Hello everyone, I've been dealing with psoriasis for about 9 years. I've tried Methotrexate and also Accutane. The latter helped significantly at first, but eventually stopped working. Now I'm supposed to start a medication called Kyntheum (active ingredient: Brodalumab). It's a biologic. Has anyon

Herein we explain how our novel data mining strategies for RNA-Seq datasets lead to new insights into the pathophysiology of psoraisis, an immune-mediated disease involving the skin. This story can also be found in [our recently published manuscript in JCI Insight.](https://insight.jci.org/articles/

I've been desperately looking into the 'cures,' making headway with recent science. As I've been going through an especially treacherous winter flare. It seems like stem cell therapies have made some profound headway in permanent remission of this disease, but unfortunately they are not legal treatm

Like the title says, I was supposed to start on Taltz but my doctor presumed that Siliq or Brodalumab would be best for me, He asked if I had any depression etc, I said I was never diagnosed but I do experience spells of depression as do anyone, I'm wondering if anyone here uses Siliq/Brodalumab an

Is IV cyclosporine 3 mg/kg, for example, the same as PO cyclosporine 3 mg/kg? It seems like many providers treat it this way, 1:1 conversion but some sources online say 3:1? Could you help explain the difference in practice vs. online sources? Thank you!

Our department hired a new NP recently and is shadowing in clinic. She was asking about cyclosporine and I made an off the cuff remark that she shouldn't be too worried because she shouldn't be prescribing it anyway (after educating her about the labs to follow, doses etc.). When she leaves she says

Yesterday I was at work, sitting at my desk looking at my computer screen. I started to notice black splotches appearing in my vision, similar to what I have seen in the past when I have stood up too fast. I have never experienced this sitting down before but I wasn't alarmed and figured I'd wait it

this is about my aunt (female, late 50s, black, high BMI) just now. her reading came down to 195/97 on the arm cuff machine we have at home but im really worried. she’s already on BP meds (and a plethora of other meds). she started a regimen of cyclosporine for membranous nephropathy(sp?) and protei

I apologize for the strained wording. I tried to Google this but I couldn't figure out the right search terms. In the US, generally health insurance will not pay for medications prescribed for non-FDA-approved/"off-label" uses, and/or for compounded medications. It is completely legal to prescribe o

Age: 64 Sex: F Primary medical issue: Mother was diagnosed with AML FLT3 TKD in September of 2021 * Current medication: Mag, Calcium+Vit D, Acyclovir * Current Care: Every other week visit with either local oncologist or nurse practitioner, every couple months telemedicine with Fred Hutch clinic

* **Age**: 26 * **Sex**: Male * **Height**: 6'2" * **Weight**: \~145lbs * **Race**: Caucasian * **Duration of complaint:** 2 years for red cell aplasia, 8 years for CVID * **Location** (Geographic and on body):Denver, CO * **Any existing relevant medical issues (if any):** Red Cell Aplasia, CVID, Hx

Hello all, I'm looking for advice/insight into my medical history. I'm a 38 year-old man, diagnosed with Autoimmune Hemolytic in Jan 2018. Since then I've relapsed twice, with the least severe episode being the last in OCT 2020. The first and last episodes were treated with oral corticosteroids, an

This is too much isn't it? I need advice!  I'm unsure which of my doctors can help me and hoping someone here can tell me which doctor to talk to, what questions to ask, and what I might be overlooking or misinterpreting. I live in East Texas. My husband has great health insurance, but we have v