Medical Disclaimer: This site provides informational comparisons only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or pharmacist before making medication decisions.
Brand names: Siliq
12.1 Mechanism of Action Brodalumab is a human monoclonal IgG2 antibody that selectively binds to human IL-17RA and inhibits its interactions with cytokines IL-17A, IL-17F, IL-17C, IL-17A/F heterodimer, and IL-25. IL-17RA is a protein expressed on the cell surface and is a required component of receptor complexes utilized by multiple IL-17 family cytokines. Blocking IL-17RA inhibits IL-17 cytokine-induced responses including the release of pro-inflammatory cytokines and chemokines.
Contraindications
6 documented side effects by frequency
7 Reddit threads analysed for BRODALUMAB
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
5 upvotes
Most discussed side effects in community
Earlier today I was browsing Reddit and stumbled [upon a post](http://www.reddit.com/r/AskReddit/comments/33ej71/disabled_people_of_reddit_what_is_something_we_do/cqkbwu7) It made me remember all I vowed to do if I ever managed rid myself of psoriasis. To this date I’ve not yet shared a whole lot
I'm currenlty engaged in a clinical trail for a new drug called "Brodalumab", am considering doing an AMA. Is there enough interest in this to warrant the AMA? My P had taken over 80-90% of my body and is now well under 5%. It has been a life changing experience and I want to tell others of the hope
Hello folks, Apologies if this is against the rules despite my reading them, I wanted to ask if folks have any experience with Leflunomide with treating psoriatic arthritis. I'm already on Brodalumab which has completely reversed the skin side but now at 35/36 I've started getting awful joint pains
Hello everyone, I've been dealing with psoriasis for about 9 years. I've tried Methotrexate and also Accutane. The latter helped significantly at first, but eventually stopped working. Now I'm supposed to start a medication called Kyntheum (active ingredient: Brodalumab). It's a biologic. Has anyon
Herein we explain how our novel data mining strategies for RNA-Seq datasets lead to new insights into the pathophysiology of psoraisis, an immune-mediated disease involving the skin. This story can also be found in [our recently published manuscript in JCI Insight.](https://insight.jci.org/articles/
I've been desperately looking into the 'cures,' making headway with recent science. As I've been going through an especially treacherous winter flare. It seems like stem cell therapies have made some profound headway in permanent remission of this disease, but unfortunately they are not legal treatm
Like the title says, I was supposed to start on Taltz but my doctor presumed that Siliq or Brodalumab would be best for me, He asked if I had any depression etc, I said I was never diagnosed but I do experience spells of depression as do anyone, I'm wondering if anyone here uses Siliq/Brodalumab an
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
14 available comparisons
Dosage Forms
Tablet
Route
Subcutaneous