Medical Disclaimer: This site provides informational comparisons only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or pharmacist before making medication decisions.
Compare BUPROPION (bupropion) and VENLAFAXINE (Venlafaxine) — clinical data, side effects, and patient experiences.
bupropion, Wellbutrin, Zyban · Atypical Antidepressant (NDRI)
How it works
12.1 Mechanism of Action The mechanism of action of bupropion is unknown, as is the case with other antidepressants. However, it is presumed that this action is mediated by noradre...
Approved for
Venlafaxine, Effexor · SNRI
How it works
Pharmacodynamics The mechanism of the antidepressant action of venlafaxine in humans is believed to be associated with its potentiation of neurotransmitter activity in the CNS. Pre...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 26 Reddit discussions
BUPROPION
54%
positive
13 threads
VENLAFAXINE
62%
positive
13 threads
% of discussions mentioning each side effect
13 Reddit threads analysed for BUPROPION
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
69 upvotes
Most discussed side effects in community
As I get older, I’m starting to become more aware of the telltale signs that my depression symptoms are getting worse. I’ve noticed that one very specific symptom is that I feel nostalgic about so many things. In a melancholy way, not a fun way. I think it’s my brain’s way of trying to comfort me by
I obviously am not cured but it’s easily my favorite one I’ve been on. I want to know if y’all have ever started a med and were just blown away!! For me, it’s Bupropion (Wellbutrin XL). It helped reduce my depression smoking and my lack of motivation. I’ve genuinely never been happier. ETA: It’s bee
I have been a reader of this sub-reddit for some time now, but it is time for me to post. I am a first generation Asian-American and I have severe depression. I am taking bupropion sr1 at 50mg. The meds work for the most part to the extent that I can function, but at times I feel a huge surge of
So as the title suggests, ive recently come out of a huge stent of depression, about 10 years worth. Because of how long ive been depressed, most of my entire personality was taken over by it. I became withddrawn, self defeating, gave up my activities and hobbies years ago because they were no long
I have been so exhausted lately that I am on the verge of dizziness some days. I get about eight hours of sleep, so I should be well rested enough, but I wake up barely able to get out of bed. It's also really cold right now, which is sapping a lot of what little energy I have left. I am trying not
After four years on a low dose of bupropion XL (100 mg) , I decided to stop taking it. My pharmacist told me to taper off slowly, so for the first 2.5 weeks I took it every 2nd day, and for the next 2.5 weeks I took it every 3rd day. The tapering process went smoothly, so I figured it was safe to st
I’ve been depressed and anxious since I was 10 (turning 22 this year..) and it almost feels like every year, I just lose a piece of myself. Every year, I lose more energy and more hope. I struggle with so much self doubt and self hatred. I wouldn’t kill myself but I often think of how great it would
I'm only 4 foot 10, and gained about 15 pounds in 4 months on mirtazapine. That is something like the equivalent of 6 or 8 dress sizes. I need to stay on the drug because of the severity of my depression and sleep dysfunction, with long covid. Over the course of 2 months I've lost 9 of those pounds,
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
13 Reddit threads analysed for VENLAFAXINE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
69 upvotes
Most discussed side effects in community
I just needed to vent about my depression and my issues with society's stance on it somewhere. I thought these were supposed to be the best years of my life? I'm not ugly, and I like to think I'm funny and friendly, so why don't people like me? I'm always alone. Always, always, always. I've spent my
Chronic fatigue. I feel so so tired and weak all the time. Brain fog so bad it is even hard to read and comprehend stuff. Insomnia. I have to take strong sedatives to sleep. I feel like death after waking up. Developed bruxism in my sleep. Noticed it only after it fvcked up all my teeth and they s
Hi all, I unfortunately, went through a tough antidepressant withdrawal from Venlafaxine, and after finding out how common the issue was I decided to get started on creating an application to help. The app is simple and just allows you to keep track of your symptoms as they come, so you can identify
*This is more of a rant than anything. I'm sorry for the formatting. I am on mobile and not really able to think clearly right now*   One month ago, I was put in a psych ward by my parents (I'm still a minor) during what was one of the worst depressive episodes I have ever had. I was physic
I am at the end of my rope right now, and I have nowhere else to go except jump. I wake up every morning wishing it would all stop, and it's my last thought before falling asleep. I am finishing up my PhD this year, but I don't have nearly the job prospects I was expecting. I am in a field as a m
*This is a super long post*, but before I started my AD I was looking for something detailed like this to see people's progressions on their meds. I had a hard time finding much, and this is why I decided to track my own progress and share after 6 weeks. Backstory: 26yr F, have had anxiety and mild
I take Venlafaxine. Just increased from 75 mg to 150 mg. I used to masturbate a lot. Not everyday...but most days. Now I have absolutely zero urge to. I’m talking to a girl now and she says that she’s a “freak” sexually. But I’m basically asexual now because of my meds. So of course.
Hi, Reddit, Over the past month, I have been weaning off of Venlafaxine, I was only on it for 3 months but it has been a debilitating experience that should be taken seriously! After a lot of research, I have noticed many people have been taking these medications for years and the withdrawal symptom
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
BUPROPION is a Atypical Antidepressant (NDRI), while VENLAFAXINE belongs to the SNRI class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles.
BUPROPION carries 4 FDA warnings. VENLAFAXINE carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.