Medical Disclaimer: This site provides informational comparisons only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or pharmacist before making medication decisions.
Compare CANAGLIFLOZIN (INVOKANA) and Semaglutide (Ozempic) — clinical data, side effects, and patient experiences.
INVOKANA, Invokana · Other
How it works
12.1 Mechanism of Action SGLT2, expressed in the proximal renal tubules, is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen. Canaglifloz...
Approved for
Ozempic, Wegovy, Rybelsus · GLP-1 Agonist
How it works
Glucagon-like peptide-1 (GLP-1) receptor agonist with 94% homology to human GLP-1. Stimulates insulin secretion, suppresses glucagon, slows gastric emptying, and reduces appetite c...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 26 Reddit discussions
CANAGLIFLOZIN
27%
positive
11 threads
Semaglutide
33%
positive
15 threads
% of discussions mentioning each side effect
11 Reddit threads analysed for CANAGLIFLOZIN
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
9 upvotes
Most discussed side effects in community
I’m just so happy i had to share somewhere. I had my test a couple days ago and got the results, been dreading but it turned out great! The medication (canagliflozin), brown rice and food control has been working the past 2 years. I know i’ll have to continue these for the rest of my life, but know
We went out to the ADA Expo in LA a couple weeks ago and wanted to share some interesting stuff we learned from a seminar on Current and Future Treatments on Diabetes [A few photos] (http://imgur.com/a/pMkDl) [SGLT-2] (http://www.forbes.com/sites/larryhusten/2013/03/29/fda-approves-first-sglt2-inh
So I am a type 2 diabetic taking Invokamet (Metformin+Canagliflozin). I like to have a drink or two with dinner here and there. ive notied though, that if I am drinking beer I get nauseous 2-3 hours after, but not after wine or liquor. Has anyone else seen side effects such as this?
I'm male, age 47, 5 foot 8, weigh about 250 pounds. Ever since going on insulin two years ago I've had a hell of a time losing weight. I also have degenerative disc disease and osteoarthritis of the spine which makes exercising difficult, but I am walking for 15 minutes every day after work, and wor
I'm wondering if anyone has started this med and could tell me how they feel about it. I'm a type 1 and it was offered to me to help lose weight. I'm just unsure of how it will change my BG, if I'll be having lots of hypos and if it really will help me lose weight. Any input would be great to hear.
I've been using Xigduo (metformin with canagliflozin) and I notice that when you eat spicy the capsaicin gets excreted through the urine as well. As a man you will end up with a spicy weiner when you pee. I am an extremely spicy eater but I thought I'd share this uncomfortable side effect for all of
https://preview.redd.it/haphqq6tm0rf1.png?width=3363&format=png&auto=webp&s=f200f3e9b7e0fb319c5fdd2a7f5ee9f1c364b214
[https://www.mdmag.com/medical-news/podcast-canagliflozin-approval-sglt2-inhibitors-bakris](https://www.mdmag.com/medical-news/podcast-canagliflozin-approval-sglt2-inhibitors-bakris)
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
15 Reddit threads analysed for Semaglutide
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
57 upvotes
Most discussed side effects in community
As I've mentioned in prior posts, I'm an untreated T2 (about 3 years now?) due to being too poor to afford health care and medications but not poor enough for assistance, but that officially ends today!!! I've been on a free CGM for 12 days and now I start Ozempic from a local program and Novo Nordi
I was diagnosed back at the end of March this year and I was very sick. My A1C was 14! Blood sugars of 300+ average. I took this very seriously as I had seen what type 1 did to my grandma. And I know type 1 and type 2 are two very different beasts, I did not want to have to give myself insulin as we
I am new diagnosed type 2 diabetic. My fasting bs was 140 and A1C is 6.4. My insurance denied both tirzepitide and Semaglutide brand names stating my A1C must be 6.5. I’m so frustrated. I had started taking compounded Semaglutide prior to my diagnosis for weight loss and then did my blood work and r
**1st June 2021 - new docs, start treatment** weight: **216 lb** / 97.98 kg height: 6'1" / 1.85 m BMI: 28.5 (overweight) BP: **132/90** (too high) *start lisinopril* HbA1c: **10.4%** average BG: 252 mg/dL, 14 mmol/L LDL: 127 mg/dL HDL: 36 mg/dL TG: 845 mg/dL (!)
I have been using ozempic for 3 months. My side effects were mild and bearable. I noticed that I got nausea when I ate unhealthy or large amounts of food. I started to eat less and better quality. I was more sensitive to motion nausea (like long bus rides), but all ok. Last month my period was
I was diagnosed with T2 in April 2024 after having symptoms like thirsty and weight loss . My A1C was 11.5 in April .after taking medications and vigorous workouts , A1C dropped to 5.5 in October . I trained for marathon and ran Chicago marathon . I put in lot of miles . I am not strict on diet tho
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
CANAGLIFLOZIN is a Other, while Semaglutide belongs to the GLP-1 Agonist class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles. CANAGLIFLOZIN is administered via Oral, whereas Semaglutide uses Subcutaneous or Oral. Route of administration can affect onset of action and patient adherence.
CANAGLIFLOZIN carries 4 FDA warnings. Semaglutide carries 3 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.