Compare CLOBAZAM (Clobazam) and TOPIRAMATE (Topiramate) — clinical data, side effects, and patient experiences.
Clobazam · Benzodiazepine
How it works
12.1 Mechanism of Action The exact mechanism of action for clobazam, a 1,5-benzodiazepine, is not fully understood but is thought to involve potentiation of GABAergic neurotransmis...
Approved for
Topiramate, Topamax · Anticonvulsant
How it works
12.1 Mechanism of Action The precise mechanisms by which topiramate exerts its anticonvulsant and preventive migraine effects are unknown; however, preclinical studies have reveale...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 26 Reddit discussions
CLOBAZAM
17%
positive
12 threads
TOPIRAMATE
21%
positive
14 threads
% of discussions mentioning each side effect
12 Reddit threads analysed for CLOBAZAM
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
6 upvotes
Most discussed side effects in community
26, female, white, 4ft 10in, ~80-90 pounds, Tuberous Sclerosis, nonverbal, seizures. My sister ^ has not been sleeping the last few weeks. Originally thought it was due to increase in CBD oil (3.5ml to 5 twice per day). Cut the CBD completely. Still was not sleeping. Started to add CBD back at 3.5m
Hello Doctors and aspiring Doctors! I need help, and I apologize because this will probably be all over the place and include some irrelevant information since I don’t know what’s relevant or not, so I’ll just be spewing everything out. My daughter is 2 years and 3 months old and she weigh 23lb-24l
We have a patient who we've compounded clobazam 1mg/mL suspension for for years and years. It's just crushed clobazam tablets in 1:1 Ora-Plus and Ora-Sweet. We compound 1 month's worth at a time. On file, it says "Expiry: 30 days" but I'm questioning where this comes from. Does anyone have any refer
Back pain on the middle-lower left side. Does not get better with exercise (weight training). Has been going on for about 2 to 3 years. Sometimes better, sometimes worse, but always gets worse with PMS and period symptoms. Meds consumed currently: (I also have bipolar disorder type 2) - divalproex s
Hi everyone, 24M here (79 KG, 5'10") from India. I’ve been living with epilepsy since 2016 and have been on various medications over the years. However, recently I’ve been dealing with some troubling symptoms after withdrawing from my epilepsy medications, and I’m looking for advice or similar exper
Age: 29 Sex: Female Height: 1.65cm / 5'5" Weight: 60kg / 132lbs Race: Caucasian Duration of complaint: n/a Location on body: CNS Diagnosed conditions: depression (possible PMDD), generalized anxiety disorder, chronic allergic rhinitis Meds: 20mg Brintellix, Qlaira, 50 000 UI Calciferol (weekly), Urb
I’m a tech at cvs. I’m familiar with processing regular TARs, for adults. I’m off today and no other tech on the team understands how to do TARs. Now, SARs for kids, on the other hand, if it’s anything close to TARs, I think I can manage. The SAR in question is for clobazam. My question is, is ther
I have epilepsy, and take Lamotrigine / Sertraline and Clobazam (Clobazam as required). The rash appears to have grown by 75% in the last 24 hours. The rash on the front seems to be directly in front of the area of most pain on my back - which feels like it’s focussed around my shoulder blade. Ca
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
14 Reddit threads analysed for TOPIRAMATE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
16 upvotes
Most discussed side effects in community
# General Info An Anticonvulsant may be used as a mood stabilizer to treat mood disorders characterized by intense and sustained mood shifts, typically Bipolar Disorder. Mood stabilizers suppress swings between mania and depression. The oldest and most studied mood stabilizer is [Lithium](https://ww
Hi all, I know this is a common question/topic of discussion here but I’m so frustrated and I’m looking for any help. I’m currently on 1200 lithium and 150 lamictal. Started 50 topiramate once a night 3 1/2 weeks ago, have seen no results, no change in appetite, nothing. I was diagnosed a year ago
So my husband turned 28 today. It's his first birthday since we got married, his first birthday in years when all our friends can hang out, he has the day off, we have our own place, and generally everything is good. Only problem is that this morning I woke up with my mania coming to a screeching ha
Hi everyone, if you’re reading this, thank you. From the deepest I can, I appreciate you. I ***finally*** got my diagnosis on the 30th of September after many years of confusion, seeing multiple counselors, therapists, doctors and psychiatrists. Earlier in the month I voluntarily spent a week in th
Hey all! I started noticing significant shedding of my hair about six months after upping my dose of topiramate to 75 mg/day. It seemed to get worse when I switched generic brands to Teva and right now about 2/3 of my hair is gone. Literally clumps were falling out on my floors and I was cleaning
It’s a mixture of bad choices influenced by a depression episode and reasons out of my control. I was fit last summer during a hypomanic episode then I went through a following depression episode last fall/winter and gained 30lb through binge eating. Hovered there. Then got meds adjusted to change t
As of late I have found it very hard to get out of the house. I can get up, shower, eat but when it finally comes time to leave; I just can’t. Going to the store is no problem, but getting out to go do something is seemingly impossible. I’ve recently went under some pretty drastic medication changes
I was prescribed it in the hospital because they didn’t think I was taking the lithium even though I was and they thought I was allergic to lamictal even though I’m not, and I refuse to take depakote, so they went with topamax, but I don’t hear of anyone taking topamax as a mood stabilizer. Everyone
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
CLOBAZAM is a Benzodiazepine, while TOPIRAMATE belongs to the Anticonvulsant class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles.
CLOBAZAM carries 4 FDA warnings. TOPIRAMATE carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.
Every figure on this comparison links back to its primary source. See data sources and methodology for the full provenance trail.