Medical Disclaimer: This site provides informational comparisons only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or pharmacist before making medication decisions.
Compare CLOZAPINE (Clozapine) and OLANZAPINE (Olanzapine) — clinical data, side effects, and patient experiences.
Clozapine, Clozaril · Atypical Antipsychotic
How it works
12.1 Mechanism of Action The mechanism of action of clozapine is unknown. However, it has been proposed that the therapeutic efficacy of Clozapine ODT in schizophrenia is mediated ...
Approved for
Olanzapine, Zyprexa, LYBALVI · Atypical Antipsychotic
How it works
12.1 Mechanism of Action The mechanism of action of olanzapine, in the listed indications is unclear. However, the efficacy of olanzapine in schizophrenia could be mediated through...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 27 Reddit discussions
CLOZAPINE
8%
positive
12 threads
OLANZAPINE
40%
positive
15 threads
% of discussions mentioning each side effect
12 Reddit threads analysed for CLOZAPINE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
127 upvotes
Most discussed side effects in community
February 24, 2025 - Beginning today, FDA does not expect prescribers, pharmacies, and patients to participate in the risk evaluation and mitigation strategies (REMS) program for clozapine or to report results of absolute neutrophil count (ANC) blood tests before pharmacies dispense clozapine. FDA st
i am taking clozapine at a high dose for my mental health. i traveled across state lines for Christmas to be with my mom and she searched my room. i used to use drugs so she does this, but she said she found my clozapine and flushed it. she doesn’t believe in any drugs, prescribed or not. I’ve been
Hi guy! I graduated in 2022 and signed with Walgreens but i just got fired - and here’s where i need your help. For the year I was there I was never issued any warnings or talked to about my performance, until one night shift I came in and the previous pharmacist had set aside an e-supply of cloza
I work LTC, the physicians are straight up refusing to re-enroll all of their patients. This is fun. 🙃 *Edit: FDA update https://www.fda.gov/drugs/drug-safety-and-availability/fda-temporarily-suspending-certain-clozapine-rems-program-requirements-ensure-continuity-care
The FDA will no longer require REMS monitoring for clozapine going forward https://www.psychiatrictimes.com/view/fda-officially-removes-rems-requirement-for-clozapine?fbclid=IwY2xjawIuKPZleHRuA2FlbQIxMQABHYf4RXJt8i4dpQOMzKOml6S3BSLRRIz_NqASLgLgu3BtAumONRfXWNycBA_aem_ZL5d8iqsfV7AaohhFkrfEw Officiatin
Had a patient come in a few weeks ago asking for strepsils, saying his throat was hurting him terribly. Our system allows me to really quickly pull up his drug list (which I do to check if they are diabetic so I don't give the sugar-containing strepsils to a diabetic). And... He's on clozapine. He's
60F, Asian, DM2, schizophrenia, currently taking Metformin, Jardiance, Vraylar, Zoloft, and Ingrezza. Hi all, I’m posting to gather some information for my mom. My mother was diagnosed with schizophrenia later on in life at around 46 years old. She was completely normal most of her life up until a
FDA approved a modification to the Clozapine REMS that will go into effect on Nov 15, 2021. Pharmacies must re-certify in the Clozapine REMS by then to continue to dispense the medication. To re-certify, see the Important Program Update at [www.clozapinerems.com](http://www.clozapinerems.com/).
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
15 Reddit threads analysed for OLANZAPINE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
179 upvotes
Most discussed side effects in community
My doctor gsve me olanzapine to aid sleep. In the perscription he specifivallly wrotr "to aid sleep". This made me think the medicine could be taken as needed, but no. My nurse found out i had skipped the sleeping pill and put me in the psycgward arguing "laxk of compliance"
Has anyone ever successfully lost their meds weight? I just seem to be getting bigger.
Risperidone made me lactate... yep Latuda made me throw up every single time I took it Olanzapine made me feel like I was drunk Seroquel made me gain 40kg and Lamotrigine gave me the rash
Celebrating weight loss after olanzapine
I couldnt read for almost 10years so maybe even longer. I didn't track the time. I was always a big reader. I finished 700page russian literature in a week. But for some reason I wasn't able to do this anymore. I could barely focus on a few Paragraphs, so I stopped reading. I tried it several times
For the first time in a very very long time I am actually proud of myself. I am now stable on Tegretol, clonidine, and olanzapine. I have a job, I was promoted to manager and even made employee of the month. I can't believe how far I've come. 7 months ago I was homeless and strung out on the streets
8 years stable now on olanzapine, but i sleep 10 hrs each day which is alot for someone who wants to study alot, i switched to abilify 20 days now, everything is good but i have insomnia from olanzapine withdrawal, how much time will it take for me to sleep normal again?
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
Both CLOZAPINE and OLANZAPINE belong to the Atypical Antipsychotic class. While they share a similar mechanism of action, differences in pharmacokinetics, dosing, and side effect profiles may make one more suitable than the other for individual patients.
CLOZAPINE carries 4 FDA warnings. OLANZAPINE carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.