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Compare DAPAGLIFLOZIN (FARXIGA) and GLIMEPIRIDE (Glimepiride) — clinical data, side effects, and patient experiences.
FARXIGA, Farxiga · Other
How it works
12.1 Mechanism of Action Sodium-glucose cotransporter 2 (SGLT2), expressed in the proximal renal tubules, is responsible for the majority of the reabsorption of filtered glucose fr...
Approved for
Glimepiride, Amaryl · Sulfonylurea
How it works
12.1 Mechanism of Action Glimepiride primarily lowers blood glucose by stimulating the release of insulin from pancreatic beta cells. Sulfonylureas bind to the sulfonylurea recepto...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 23 Reddit discussions
DAPAGLIFLOZIN
20%
positive
15 threads
GLIMEPIRIDE
13%
positive
8 threads
% of discussions mentioning each side effect
15 Reddit threads analysed for DAPAGLIFLOZIN
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
14 upvotes
Most discussed side effects in community
I’m honestly so happy I’m not even sure how I feel. Back in July I unexpectedly found out I was diabetic after finding a high amount of sugar in my urine and being urged to go to the ER for immediate bloodwork. I’ve been put on 5mg of Farxiga (dapagliflozin) the last month or so and have been keepi
I used to take Xigduo and it was covered just fine on my previous insurance, but then I lost my job and had to get a plan off the healthcare marketplace. They have a fairly large deductible for prescriptions and charge coinsurance on name-brand drugs, so even after using a manufacturer's coupon I'd
http://www.fda.gov/Drugs/DrugSafety/ucm505860.htm The U.S. Food and Drug Administration (FDA) has strengthened the existing warning about the risk of acute kidney injury for the type 2 diabetes medicines canagliflozin (Invokana, Invokamet) and dapagliflozin (Farxiga, Xigduo XR). Based on recent repo
So I just got my first CGM and I'm loving it! Previously, I was finger pricking and noticed that my waking BG was always higher than it was the rest of the day. I suspected Dawn Phenomenon, as it would be 120 odd and then settle down to 80-90 throught the day, with the odd spike upt to 120-140 after
I am 34 F , I have put on weight ( 13 kgs or 30 pounds ) steadily over the last 3-4 years post covid. Current weight is 94kg or 207 pounds at 166cm height. My HB1AC is 6.4 which my doctor said is on the border. I have high LDL cholesterol at 214. HOMA IR is 3.6 so I have insulin sensitivity. My do
I know 6 days is a small window, but hear me out. Diabetic for 9 years. Maintained it below 7 till 6 months back. Met with accident on 6th Oct, thumb got amputated just below nail. Found out during surgery blood tests Hba1c was 8 ( stress and stress eating in last 6 months pushed it up). Surgeon s
Hi, my dad (58) was diagnosed with Type 2 diabetes almost a year ago. My dad drinks alcohol occasionally and is a non-smoker. Last December 6, 2024, his HbA1c increased from 7.5 to 8.1. We were a bit complacent with my dad's diet, and as a family of 5, we also had some lapses. We want to be stricter
Hi everyone, well I had a terrible year last year which brought on a huge amount of stress, due to mental health issues with my daughter and also working in a high pressured environment. I am a self-employed consultant so I have to work as I am the main breadwinner for the family. My diabetic contr
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
8 Reddit threads analysed for GLIMEPIRIDE
Overall Sentiment
Slightly negative
Comparison Threads
0
Avg Post Score
53 upvotes
Most discussed side effects in community
I am a type 2 diabetic. Last July, right before I started keto my doc was rumbling about me "graduating" to insulin. He had added glimepiride and Januvia, and my A1C had still crept north of 7. I began keto on July 9th. Since then, with 40 pounds gone we eliminated glimepiride, then januvia, and mid
Hello, My dad (77M, male) attempted suicide yesterday. He fell from a 12-foot balcony. He was admitted to the ER and has three primary injuries. A broken hip, where his right leg meets the hip. Bruising to the abdominal aorta. And a fractured vertebrae (C6)/out of place disk in the neck (C6). He is
The following post does not constitute medical advice. If anything in here is interesting to you, talk to your endocrinologist. I just wanted to give my personal experience of being on Metformin for approximately 14 years. For context, I am an insulin-dependent diabetic and a thyroid cancer surviv
Good morning folks. I am seeking advice for people who have maybe been in a similar situation. In my office of apps and one doc, we are assigned partners and share an office with said partner. The person on call for the week also covers for the doc if need be. Coverage includes signing off on injec
First published last Wednesday, 18th of March. Following a rapid increase in popularity of GLP-1 drugs for diabetes and weight loss, such as semaglutide and tirzepatide, approximately one in eight U.S. adults now take these medications, which also provide cardiovascular benefits. However, when patie
I had some pain in my bladder before Christmas and went to an Urgent Care place. I had been drinking half a gallon of water a day for two months and the doctor thought that maybe it was the increase in drinking that was making my bladder hurt, since my "urine had no sugar and no ketones" in it. Fast
Hey folks, I’m on day 4 of doing a Keto Chow–only diet (just the shakes, around 1650 cals/day), and even though I’ve been super low carb, I’m still waking up with really high blood sugar. About 160–180 every morning. (Note, I have ben low carb for about three months now and did this experiment speci
Hello guys I hope all of you are doing good. I was diagnosed last year in December my hba1c was 11.5 and I am just 28. So doctor put me on metformin 500 mg and glimepiride 1mg. Every 15 days we did sugar and blood report for fbs and ppbs. Within two months it was under control. So doctor did an exp
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
DAPAGLIFLOZIN is a Other, while GLIMEPIRIDE belongs to the Sulfonylurea class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles.
DAPAGLIFLOZIN carries 4 FDA warnings. GLIMEPIRIDE carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.