DISULFIRAM vs TOPIRAMATE

Hi guys! I know that in school we were taught that Flagyl and alcohol use produced a disulfiram reaction but in PUBMED they did a study in 2020 with a double-blind, placebo-controlled study in 12 people (I know the sample size is low) and " found no difference in aldehyde dehydrogenase levels betwe

I ordered some groceries today, but someone made a mistake. Instead of fruits, snacks, non-alcoholic beers, and other beverages, the courier delivered 6 bottles of regular beer and a package of potato chips. I thought I had my addiction under control; I even posted today about being sober for 50 da

[Our Medical Director found these picture perfect poisonous mushrooms \(amanita muscaria\) in our parking lot.](https://preview.redd.it/3qdgczps6w1e1.png?width=647&format=png&auto=webp&s=1b45eed3dd752f30f7ed1cfdbd117cefee93a4d7) At the Poison Center, we say “all mushrooms are edible, som

*Long text* For the past decade, I’ve dedicated my life to researching, understanding, and overcoming chronic illness—primarily Lyme/Babesia infections and severe Candida overgrowth. My journey has been long and difficult, but I want to share what I’ve learned in the hope that it helps others. I’ve

It has been quite a journey, and I would be remiss if I did not thank this community for taking part in it alongside me. Over the last two years, and in the years before when I would quit for days, weeks, and months on end, I learned that there is no quick fix, no catch-all solution that can be appl

been in rehab many times (OUD) and fear a lot of people here don’t really know how it works in AA cuz you’re all breaking anonymity by saying you’ve seen him in a meeting 😭😭😭 homie is scared of the law and may be an unpopular opinion but i hope he stays sober throughout this legal process and lea

I am on rotations and I heard a pharmacist counseling on this. However, there have been reviews of the data and no apparent connection has been made. Apparently that was all based on a few case studies and the MOA doesn't suggest that it would cause disulfiram-like reaction. I know we've all heard t

Yesterday a patient's insurance (!!!) caught a drug interaction (he doesn't get the Disulfiram from my pharmacy, but bills it through the same insurance). This was a HARD STOP, pharmacist could not override type of interaction alert. Apparently Fluticasone nasal spray (Flonase) has a small amou

# General Info An Anticonvulsant may be used as a mood stabilizer to treat mood disorders characterized by intense and sustained mood shifts, typically Bipolar Disorder. Mood stabilizers suppress swings between mania and depression. The oldest and most studied mood stabilizer is [Lithium](https://ww

Hi all, I know this is a common question/topic of discussion here but I’m so frustrated and I’m looking for any help. I’m currently on 1200 lithium and 150 lamictal. Started 50 topiramate once a night 3 1/2 weeks ago, have seen no results, no change in appetite, nothing. I was diagnosed a year ago

So my husband turned 28 today. It's his first birthday since we got married, his first birthday in years when all our friends can hang out, he has the day off, we have our own place, and generally everything is good. Only problem is that this morning I woke up with my mania coming to a screeching ha

Hi everyone, if you’re reading this, thank you. From the deepest I can, I appreciate you. I ***finally*** got my diagnosis on the 30th of September after many years of confusion, seeing multiple counselors, therapists, doctors and psychiatrists. Earlier in the month I voluntarily spent a week in th

Hey all! I started noticing significant shedding of my hair about six months after upping my dose of topiramate to 75 mg/day. It seemed to get worse when I switched generic brands to Teva and right now about 2/3 of my hair is gone. Literally clumps were falling out on my floors and I was cleaning

It’s a mixture of bad choices influenced by a depression episode and reasons out of my control. I was fit last summer during a hypomanic episode then I went through a following depression episode last fall/winter and gained 30lb through binge eating. Hovered there. Then got meds adjusted to change t

As of late I have found it very hard to get out of the house. I can get up, shower, eat but when it finally comes time to leave; I just can’t. Going to the store is no problem, but getting out to go do something is seemingly impossible. I’ve recently went under some pretty drastic medication changes