Medical Disclaimer: This site provides informational comparisons only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or pharmacist before making medication decisions.
Compare EXENATIDE (Byetta) and Semaglutide (Ozempic) — clinical data, side effects, and patient experiences.
Byetta, Bydureon · GLP-1 Agonist
How it works
12.1 Mechanism of Action Incretins, such as glucagon-like peptide-1 (GLP-1), enhance glucose-dependent insulin secretion and exhibit other antihyperglycemic actions following their...
Approved for
Ozempic, Wegovy, Rybelsus · GLP-1 Agonist
How it works
Glucagon-like peptide-1 (GLP-1) receptor agonist with 94% homology to human GLP-1. Stimulates insulin secretion, suppresses glucagon, slows gastric emptying, and reduces appetite c...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 24 Reddit discussions
EXENATIDE
22%
positive
9 threads
Semaglutide
33%
positive
15 threads
% of discussions mentioning each side effect
9 Reddit threads analysed for EXENATIDE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
65 upvotes
Most discussed side effects in community
60yr SW 95kg GW 70kg After 5 months I’ve achieved my goal weight. I’ve not been this weight since a teenager. Tried every diet over the years but only had temporary success. Always struggled with food noise. Retired early as a GP in the UK due to MH in 2022. Turned 60 earlier this year & finall
I'm just curious. The more I experience this pain and weakness the more I realize this is what sleep deprivation is. Without proper restorative sleep you get the exact same symptoms. Poorer sleep leads to a disruption in hormonal levels which makes sense why this affects more women then men. They
I just finished reading an *excellent* series of blog posts about how the fear of insulin is mostly bullshit. I wanted to understand the articles better, and contribute to fittit, so I went through each article and summarized them the best as I could in layman terms. All of them are worth a read, an
Since we can't submit links on this sub, I'm pasting an interesting article I saw today. It's by Sarah Zhang for the Atlantic. Did Scientists Accidentally Invent an Anti-addiction Drug? People taking Ozempic for weight loss say they have also stopped drinking, smoking, shopping, and even nail biting
Fair warning: this will be a long post filled with data and graphs and some potentially controversial commentary. You may feel the urge to express how I am doing something wrong, not eating enough, etc. I’ve seen and read it all so it will fall on deaf ears here, but have at it I suppose. I plan to
My health plan formulary updates for GLPS! As a PA tech, not looking forward to alllllll the calls and PAs we’re about to get lol -GLP medications for diabetes will require step-therapy on October 1 2023. This update applies to dulaglutide (Trulicity), exenatide (Bydureon and Byetta), liraglutide (
Invex Therapeutics # Background Invex Therapeutics is a clinical stage biopharmaceutical company incorporated on the 8th of March in 2019 which is repurposing an orphan drug (Exenatide) for initial use in the indication of Idiopathic Intracranial Hypertension (IIH). A basic understanding of the sc
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
15 Reddit threads analysed for Semaglutide
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
57 upvotes
Most discussed side effects in community
As I've mentioned in prior posts, I'm an untreated T2 (about 3 years now?) due to being too poor to afford health care and medications but not poor enough for assistance, but that officially ends today!!! I've been on a free CGM for 12 days and now I start Ozempic from a local program and Novo Nordi
I was diagnosed back at the end of March this year and I was very sick. My A1C was 14! Blood sugars of 300+ average. I took this very seriously as I had seen what type 1 did to my grandma. And I know type 1 and type 2 are two very different beasts, I did not want to have to give myself insulin as we
I am new diagnosed type 2 diabetic. My fasting bs was 140 and A1C is 6.4. My insurance denied both tirzepitide and Semaglutide brand names stating my A1C must be 6.5. I’m so frustrated. I had started taking compounded Semaglutide prior to my diagnosis for weight loss and then did my blood work and r
**1st June 2021 - new docs, start treatment** weight: **216 lb** / 97.98 kg height: 6'1" / 1.85 m BMI: 28.5 (overweight) BP: **132/90** (too high) *start lisinopril* HbA1c: **10.4%** average BG: 252 mg/dL, 14 mmol/L LDL: 127 mg/dL HDL: 36 mg/dL TG: 845 mg/dL (!)
I have been using ozempic for 3 months. My side effects were mild and bearable. I noticed that I got nausea when I ate unhealthy or large amounts of food. I started to eat less and better quality. I was more sensitive to motion nausea (like long bus rides), but all ok. Last month my period was
I was diagnosed with T2 in April 2024 after having symptoms like thirsty and weight loss . My A1C was 11.5 in April .after taking medications and vigorous workouts , A1C dropped to 5.5 in October . I trained for marathon and ran Chicago marathon . I put in lot of miles . I am not strict on diet tho
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
Both EXENATIDE and Semaglutide belong to the GLP-1 Agonist class. While they share a similar mechanism of action, differences in pharmacokinetics, dosing, and side effect profiles may make one more suitable than the other for individual patients. EXENATIDE is administered via Subcutaneous, whereas Semaglutide uses Subcutaneous or Oral. Route of administration can affect onset of action and patient adherence.
EXENATIDE carries 4 FDA warnings. Semaglutide carries 3 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.