LABETALOL vs LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE

Labetalol changes its affinity for alpha and beta receptors based on the route that it is administered. I am wondering if there are other drugs out there that have different pharmacology based on their route of administration?

Am I working at the last pharmacy in the country that does this? I don't mind getting used to it because I know it's the preference of the elderly pharmacy owner, and it's a great place to work. I just started there and there is enough to learn without having to look up the brand name for trihexyph

I recently finished my rotation on a medicine ward. On the last day, I was on rounds with the residents/med students and we had a pregnant lady admitted for acute hepatitis. They talked about potential causes and investigations, we told them to be careful about upping her morphine too much due to he

I am losing my mind over this. Would it be labetalol, NTG, or nicardipine? I thought yoy wpuld not use labetalol because it is a beta blocker, and not use NTG bc it woukd lower BP too quickly. so I picked nicardipine. however labetalol has both alpha and beta blocking so apparently that was the answ

Beta blockers are still prescribed as monotherapy for hypertension, especially in older patients who have been on them for many years. The kinetics of, say, metoprolol succinate are quite different from IV metoprolol, and runs of bradycardia are an issue with the latter in a patient of normal heart

Does anyone have a good potency analogy to explain that drug strengths cannot be directly compared to other drugs? I had a patient that was afraid to take labetalol 200mg because it was “higher than 10mg of lisinopril.” I’m admittedly really bad at translating stuff into layman’s terms and I did th

Yeah so thats pretty much it, anyone know where i can find stuff abt the drug discovery process for labetalol? Much appreciated

I am so fucking tired of the discrimination that women face when it comes to medical treatment. From being gaslighted, denied therapy or misdiagnosed, this discrimination often costs women their lives. One particular horrible mistreatment of women is the performance of gynecological procedures witho

So I was telling an acquaintance about this and he thought it was pretty interesting, so I thought I would share it with you guys. About 6 years ago my friend and I were on our way to pick up another friend from work at around 10pm. He was the driver and I was the passenger. We approach the intersec

I need some advice/ guidance. I am a male in my mid 20s and I went to a dentist to have a filling done on my back molar. The dentist applied lidocaine and did an injection into my gums on the upper right side. That was the last thing I remember. The next thing I know I am being pushed out in a gurne

I’ve been wanting to write this out and share my story for a while. I finally did. Here’s the very true and very real story: It was February 15th. 2018. The day after Valentine’s Day (which fell on a Thursday.) I was a little depressed during that whole week. But that is beyond the point of this sto

Ten years ago I got a copper IUD inserted. I did it at Planned Parenthood because, at the time, I worked for a school that relied on that bullshit Hobby Lobby stuff to not cover any birth control. This is no way a knock against Planned Parenthood, which is out here doing vital work, but the experien

I was curious if anyone working on the hospital side of things would be willing to share any ideas or solutions for managing the lidocaine/epinephrine drug shortage? Currently playing with the idea of compounding the product from stock epinephrine and lidocaine with the intent of packaging and stor

Basically, it’s compounded as a cream or gel, 6%lidocaine : 0.02% epinephrine: 4% tetracaine The epinephrine is essential in this compound as it leaves a “halo” of “numbing” but also aids in the procedure. Apparently there’s a shortage and there seems to be no conclusive answer, what does the phar