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Brand names: Labetalol Hydrochloride, Trandate
Pharmacodynamics The capacity of labetalol hydrochloride to block alpha receptors in man has been demonstrated by attenuation of the pressor effect of phenylephrine and by a significant reduction of the pressor response caused by immersing the hand in ice-cold water (“cold pressor test”). Labetalol hydrochloride’s beta 1 - receptor blockade in man was demonstrated by a small decrease in the resting heart rate, attenuation of tachycardia produced by isoproterenol or exercise, and by attenuation o
Contraindications
7 documented side effects by frequency
7 Reddit threads analysed for LABETALOL
Overall Sentiment
Mixed
Comparison Threads
1
Avg Post Score
21 upvotes
Threads directly comparing LABETALOL to other medications
Labetalol changes its affinity for alpha and beta receptors based on the route that it is administered. I am wondering if there are other drugs out there that have different pharmacology based on their route of administration?
Am I working at the last pharmacy in the country that does this? I don't mind getting used to it because I know it's the preference of the elderly pharmacy owner, and it's a great place to work. I just started there and there is enough to learn without having to look up the brand name for trihexyph
I recently finished my rotation on a medicine ward. On the last day, I was on rounds with the residents/med students and we had a pregnant lady admitted for acute hepatitis. They talked about potential causes and investigations, we told them to be careful about upping her morphine too much due to he
I am losing my mind over this. Would it be labetalol, NTG, or nicardipine? I thought yoy wpuld not use labetalol because it is a beta blocker, and not use NTG bc it woukd lower BP too quickly. so I picked nicardipine. however labetalol has both alpha and beta blocking so apparently that was the answ
Beta blockers are still prescribed as monotherapy for hypertension, especially in older patients who have been on them for many years. The kinetics of, say, metoprolol succinate are quite different from IV metoprolol, and runs of bradycardia are an issue with the latter in a patient of normal heart
Does anyone have a good potency analogy to explain that drug strengths cannot be directly compared to other drugs? I had a patient that was afraid to take labetalol 200mg because it was “higher than 10mg of lisinopril.” I’m admittedly really bad at translating stuff into layman’s terms and I did th
Yeah so thats pretty much it, anyone know where i can find stuff abt the drug discovery process for labetalol? Much appreciated
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13 available comparisons
Dosage Forms
Tablet
Route
Oral