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Brand names: apixaban, Eliquis
12.1 Mechanism of Action Apixaban is a selective inhibitor of FXa. It does not require antithrombin III for antithrombotic activity. Apixaban inhibits free and clot-bound FXa, and prothrombinase activity. Apixaban has no direct effect on platelet aggregation, but indirectly inhibits platelet aggregation induced by thrombin. By inhibiting FXa, apixaban decreases thrombin generation and thrombus development.
Contraindications
7 documented side effects by frequency
7 Reddit threads analysed for APIXABAN
Overall Sentiment
Mixed
Comparison Threads
1
Avg Post Score
152 upvotes
Most discussed side effects in community
Threads directly comparing APIXABAN to other medications
**🛎️ DING 🛎️ DING 🛎️ DING** Clinicians… **Are.** **You.** **Ready?** For a fight messier than ward politics… For a battle bloodier than supratherapeutic INR… For a tussle rougher than back-to-back night shifts… For the very first time, two clot-stopping heavyweights step into the ring.
Okay, so picture this: you’re the stroke consultant. You have a patient with recurrent ischaemic stroke. You’ve *already* covered them with clopidogrel. What more can you do 🤔? Your apixaban is collecting dust because the patient doesn’t have AF. So the PA asks “Hey, what if we gave this patient a
(I'm on inpatient neurology now...) What cause of intracranial hemorrhage is treated with tPA? >!Venous sinus thrombosis!< What drug can you use to treat migraine in pregnancy? >!Botox injections!< What is the effect of pregnancy on migraines? >!Makes migraines less severe!< The "v
Time to quiz you little nerds … who can tell me how long we treat a ***provoked*** VTE for? …Anyone?? To the trained *Passmed* monkeys who blurted “3 months!”, well done. Have a cookie 🍪 But just pause that Pavlovian hand-raise for a sec. **Why** ***three*** **months?** Why not two? or four? http
**Background:** Hi everyone! I’m a foreign pharmacy graduate from the Philippines who graduated in 2020 and moved to the US in 2021. From there I started working as a full-time hospital pharmacy technician, passed the FPGEE in 2022, completed internship hours in 2023, and recently passed the NAPLEX
Okay, so picture this: you’re the stroke consultant. You have a patient with recurrent ischaemic stroke. You’ve *already* covered them with clopidogrel. What more can you do 🤔? Your apixaban is collecting dust because the patient doesn’t have AF. So the PA asks “Hey, what if we gave this patient a
UPDATE: I PASSED 😭😭😭😭 I took the test yesterday, and honestly, it felt pretty random. It was confusing rather than difficult. Some of the tables were hard to read or figure out. There were also a few weird management questions with vague answer choices.Time was really tight — I’d definitely reco
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
6 available comparisons
Dosage Forms
Tablet
Route
Oral