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Brand names: Leqvio
Small interfering RNA (siRNA) that silences PCSK9 mRNA in hepatocytes, providing long-lasting LDL-C reduction with twice-yearly dosing.
11 documented side effects by frequency
6 Reddit threads analysed for Inclisiran
Overall Sentiment
Mixed
Comparison Threads
1
Avg Post Score
19 upvotes
Threads directly comparing Inclisiran to other medications
Hi all, Posting on behalf of my mom (F55). She has familial cholesterol and is unable to take statin meds (due to adverse reaction that effects her muscles) so she was put on rapatha injections that are done every 2 weeks. This is the only option we had in Canada and she was having significant side
​ Some of you may remember me from [This Post](https://www.reddit.com/r/wallstreetbets/comments/dv83sb/arwr_will_be_the_next_top_pharmaceutical_company/?utm_source=share&utm_medium=web2x) where I talked about ARWR when it was sitting around $40 before it broke out and hit an ATH of $7
**47M with CAC 743** – Looking for Perspective I’m a 47-year-old male who recently had a coronary artery calcium (CAC) score of 743.9 (Agatston), which puts me >90th percentile for my age/sex. # CAC Breakdown: * Left Main: 146.0 * LAD: 171.5 * LCx: 237.1 * RCA: 189.4 * PDA: 0 Report impression:
**ALNY** ALNY is our top pick for 2022 as it nears a key inflection point: APOLLO-B data of patisiran in TTR-CM (mid- 22). This is set up for success given precedent cardiac subset data from TTR-PN trials. We model $2B+ sales for patisiran/vutrisiran in TTR-CM achievable given current $2B sales of
I have a stent and my numbers are not ideal LDL hovers between 90-110. However, HDL is 70 and Tryglicerides are very good (38 last time I checked). I take Crestor 20 mg. With life style and diet this is the best I can get. The doctor pushes me to do something to get LDL under 70. Here's where I stan
This is an automatic summary, [original](http://www3.imperial.ac.uk/newsandeventspggrp/imperialcollege/newssummary/news_17-3-2017-14-40-10) reduced by 78%. ***** > The first in a new class of gene-silencing drugs, known as inclisiran, has halved cholesterol levels in patients at risk of cardiovas
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10 available comparisons
Dosage Forms
Tablet
Route
Oral