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Brand names: Xarelto, XARELTO
12.1 Mechanism of Action XARELTO is a selective inhibitor of FXa. It does not require a cofactor (such as Anti-thrombin III) for activity. Rivaroxaban inhibits free FXa and prothrombinase activity. Rivaroxaban has no direct effect on platelet aggregation, but indirectly inhibits platelet aggregation induced by thrombin. By inhibiting FXa, rivaroxaban decreases thrombin generation.
Contraindications
7 documented side effects by frequency
5 Reddit threads analysed for RIVAROXABAN
Overall Sentiment
Slightly positive
Comparison Threads
0
Avg Post Score
152 upvotes
Most discussed side effects in community
Saw that someone was requesting some useful trials to know for IM and thought I'd post this little summary I made a while back. Didn't post it because I didn't think it was fully ready and I was hoping to make a video on it but it seems like now would be a good timing. Hopefully it's useful to some
Last fall when the SPRINT results came in, I thought it seemed strange for a major trial to find something unexpected on a question that has been so thoroughly investigated previously. Now, it turns out, there was a reason for it - an unconventional means of measuring blood pressure, and one that w
Hello everyone! I passed NCLEX in 85 questions around a week ago and then I just rested almost the whole week. I didn't realized how exhausted I was until I was done with the test, but I feel amazing now! I want to share with you guys what I studied for around a month up until the day I took the tes
*How it works and what targets* The Promise of Factor XI Hiding in Plain Sight: Factor XI as a Potentially Attractive Therapeutic Target It has long been believed that reducing thrombosis (harmful blood clotting) and hemostasis (healthy blood clotting) are so closely connected that reducing clots w
Patient hgb 5.9 RBC 2.92 ( he got 2 units of blood) now Hgb 8 RBC 3.4 Based on Padua Score (5points) I should give DVT prophylaxis? altho we stopped Rivaroxaban and aspirin due to anemia.. should I re-initiate or risk vs benefit ?
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6 available comparisons
Dosage Forms
Tablet
Route
Oral