Edoxaban vs RIVAROXABAN

**Clerking the Surgical Patient** Well, it’s finally happened. You're on your first surgical on-call. You’re alone in SAU; the only point of call for every surgical nurse in the hospital. Probably the region. You’ve got someone in room one with belly pain, someone in room 2 with a wound issue, and a

Hi all. 30F, had a minor PE at 29 in May of 2025. Found it in a VQ scan they did to test for asthma after 8+ months of me complaining about extreme shortness of breath. No surgery. Unprovoked. Been on blood thinners since May 2025 (rivaroxaban), but in June/July switched to edoxaban because of extr

Any hospital pharmacists who have recently researched this topic know when the drug is going to be released? This is the much anticipated rivaroxaban/apxiaban reversal agent that has been talked about for quite some time (similar to praxbind- dabigatran’s reversal). The last I heard, last august

According to the 1/2 lives in the package insert, this doesnt really match up. Does it have more to do with protein binding? Thanks.

Does anyone know why they are dosed the way they are with regards to the lead in phase? Rivaroxaban has high dose for 21 days, Apixiban has high dose for 7 days, Edoxaban and Dabigatran both have to have a 5-10 day lead in with parenteral anticoagulation... I know "that's how the studies did it", bu

I've been on Xarelto a week. I've noticed that I get lightheaded and get a headache soon after taking each pill. I'm currently taking 15 mg twice daily. In two weeks I switch to 20 mg once a day. This has gotten worse each day. I read that the lightheadedness isn't uncommon, and saw a study that sug

Anyone else ever come across this interaction? Patient was prescribed the erythromycin for an IE of COPD. Patient was taking 60mg once daily of Lixiana (edoxaban) which is contraindicated with erythromycin here in Ireland due to CYP inhibition. They were penicillin allergic was wondering what alter

Saw that someone was requesting some useful trials to know for IM and thought I'd post this little summary I made a while back. Didn't post it because I didn't think it was fully ready and I was hoping to make a video on it but it seems like now would be a good timing. Hopefully it's useful to some

Last fall when the SPRINT results came in, I thought it seemed strange for a major trial to find something unexpected on a question that has been so thoroughly investigated previously. Now, it turns out, there was a reason for it - an unconventional means of measuring blood pressure, and one that w

Hello everyone! I passed NCLEX in 85 questions around a week ago and then I just rested almost the whole week. I didn't realized how exhausted I was until I was done with the test, but I feel amazing now! I want to share with you guys what I studied for around a month up until the day I took the tes

*How it works and what targets* The Promise of Factor XI Hiding in Plain Sight: Factor XI as a Potentially Attractive Therapeutic Target It has long been believed that reducing thrombosis (harmful blood clotting) and hemostasis (healthy blood clotting) are so closely connected that reducing clots w

Patient hgb 5.9 RBC 2.92 ( he got 2 units of blood) now Hgb 8 RBC 3.4 Based on Padua Score (5points) I should give DVT prophylaxis? altho we stopped Rivaroxaban and aspirin due to anemia.. should I re-initiate or risk vs benefit ?