Edoxaban

**Clerking the Surgical Patient** Well, it’s finally happened. You're on your first surgical on-call. You’re alone in SAU; the only point of call for every surgical nurse in the hospital. Probably the region. You’ve got someone in room one with belly pain, someone in room 2 with a wound issue, and a

Hi all. 30F, had a minor PE at 29 in May of 2025. Found it in a VQ scan they did to test for asthma after 8+ months of me complaining about extreme shortness of breath. No surgery. Unprovoked. Been on blood thinners since May 2025 (rivaroxaban), but in June/July switched to edoxaban because of extr

Any hospital pharmacists who have recently researched this topic know when the drug is going to be released? This is the much anticipated rivaroxaban/apxiaban reversal agent that has been talked about for quite some time (similar to praxbind- dabigatran’s reversal). The last I heard, last august

According to the 1/2 lives in the package insert, this doesnt really match up. Does it have more to do with protein binding? Thanks.

Does anyone know why they are dosed the way they are with regards to the lead in phase? Rivaroxaban has high dose for 21 days, Apixiban has high dose for 7 days, Edoxaban and Dabigatran both have to have a 5-10 day lead in with parenteral anticoagulation... I know "that's how the studies did it", bu

I've been on Xarelto a week. I've noticed that I get lightheaded and get a headache soon after taking each pill. I'm currently taking 15 mg twice daily. In two weeks I switch to 20 mg once a day. This has gotten worse each day. I read that the lightheadedness isn't uncommon, and saw a study that sug

Anyone else ever come across this interaction? Patient was prescribed the erythromycin for an IE of COPD. Patient was taking 60mg once daily of Lixiana (edoxaban) which is contraindicated with erythromycin here in Ireland due to CYP inhibition. They were penicillin allergic was wondering what alter