TRAZODONE HCL

Atypical Antidepressant

Brand names: Trazodone HCL

Oral

Mechanism of Action

Other agent

Indications

Trazodone hydrochloride tablets

USP are indicated for the treatment of major depressive disorder (MDD) in adults.

Contraindications

• Trazodone hydrochloride tablets are contraindicated in: Patients taking
• or within 14 days of stopping
• monoamine oxidase inhibitors (MAOIs)
• including MAOIs such as linezolid or intravenous methylene blue
• because of an increased risk of serotonin syndrome [see Warnings and Precautions (5.2)

FDA Warnings

The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, and St
The concomitant use of trazodone with MAOIs is contraindicated
If concomitant use of trazodone with other serotonergic drugs is clinically warranted, inform patients of the increased risk for serotonin syndrome and monitor for symptoms
Trazodone should also be avoided in patients with a history of cardiac arrhythmias, as well as other circumstances that may increase the risk of the occurrence of torsade de pointes and/or sudden death, including symptomatic bradycardia, hypokalemia or hypomagnesemia, and the presence of congenital prolongation of the QT interval

Known Side Effects

13 documented side effects by frequency

Drug Not Working

>10%

Fatigue

1-10%

Nausea

1-10%

Headache

1-10%

Diarrhea

1-10%

Vomiting

1-10%

Insomnia

1-10%

Depression

1-10%

Shortness of Breath

1-10%

Dizziness

1-10%

Falls

1-10%

Weakness

0.1-1%

Anxiety

0.1-1%

Community Discussions

No community discussions found for TRAZODONE HCL yet.

Compare With

7 available comparisons

Formulations

Dosage Forms

Tablet

Route

Oral