Medical Disclaimer: This site provides informational comparisons only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or pharmacist before making medication decisions.
Compare AMLODIPINE (amlodipine) and Losartan (Cozaar) — clinical data, side effects, and patient experiences.
amlodipine, Norvasc, Exforge HCT · ARB
How it works
12.1 Mechanism of Action The active ingredients of amlodipine, valsartan and hydrochlorothiazide tablets target 3 separate mechanisms involved in blood pressure regulation. Specifi...
Approved for
Cozaar · ARB (Angiotensin II Receptor Blocker)
How it works
Selectively blocks the binding of angiotensin II to the AT1 receptor found in many tissues, reducing vasoconstriction, aldosterone secretion, and sympathetic activity.
Approved for
Estimated frequency (%) based on clinical trial data
Based on 30 Reddit discussions
AMLODIPINE
27%
positive
15 threads
Losartan
7%
positive
15 threads
% of discussions mentioning each side effect
15 Reddit threads analysed for AMLODIPINE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
71 upvotes
Most discussed side effects in community
From 200+ BP to Controlled Levels of 100-120: My Journey as a 22-Year-Old with Severe Hypertension I’m 22 and recently discovered I had severe hypertension with blood pressure readings in the 200s. It’s possible I lived with those dangerous numbers for years without realizing it. For as long as I c
Back in April, I stopped taking my meds after 21 years (360mg of Valsartan + 5mg Amlodipine) because I was tired of taking pills every day, and I wanted to break free from our backwards "sickcare" system. I've long suspected that the bp meds cause us to become dependent on them, and since they do n
35 male with high BP my entire life Been on it for 1 year and 5 months. Started at 5 mg for like 3 or 6 months then went to 10 mg. Seems I have a barrage of symptoms I’ve never had before in my life for the last 6 months. Extreme daytime sleepiness***** The chills like 15 times a day ***** Swollen
I've been on Amlodipine and Carvedilol since June of 2025. I tried to stop Amlodipine without doctor's approval because it makes my anxiety worse. I tried to move up my next doctor's appointment to see if I can switch to something else like an Ace Inhibitor, but the closest they could slot me in was
About a month ago I was hospitalized. I was driving with my daughter and suddenly felt shortness of breath, dizziness and the feeling like I was going to pass out. I pulled over caught my breath and out of pure adrenaline was able to make it home and call an ambulance when they came my BP was 198/12
I was hungover, ate prosciutto, hands were shaking like crazy. I thought I'd measure it just for the fun of it. It wasn't fun when the numbers never in 10 measurement went lower than 210/120, going to the ER made things worse. It was all in my head. But we fixed it. Hell started. 2 months passed and
Just wanted to brag on myself a bit here. Since February I've been taking GLP-1 and I'm down 45lbs (247-202). My GW is 170 so I still have a ways to go but recently I've been having weird dizzy spells when bending down and standing back up. There are a lot of potential causes of course, but my BP ha
Been on medication for high blood pressure for about 4 years now, and finally found a cocktail of meds that seems to be working for me: Bisoprolol 2.5mg tablets Indapamide 1.5mg modified-release tablets Amlodipine 10mg tablets Ramipril 10mg tablets Spironolactone 25mg tablets Systolic still high but
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
15 Reddit threads analysed for Losartan
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
60 upvotes
Most discussed side effects in community
I’m a 32M and went almost my entire 20s not worrying about or even checking my blood pressure. When I was 30 I began having tachycardia episodes with high blood pressure readings which I had to go to ER for 3 times in a period of a few months with my readings at around 190/100 I got on losartan 100
Today went to see my cardiologist and no longer need to take losartan nor atorvastatin ! Got to a healthy weight and good diet that he said I no longer need the medication. Hopefully I can stay off it from now on. Im 5,8 went from 225lbs down to 185, eating a lot of food with high sodium to no/low
Hello all. I’ve been diagnosed with hypertension since 2021. I take losartan 12.5 mg 2x day, hydralazine 100mg 3x day , Carvedilol/coreg 25mg 2x day, amlodipine/norvasc 10mg 1x day (mornings), aspirin 324mg 1x day and a vitamin b12 as directed by my doctor. Yesterday I stood up and went into the kit
Hi, how is it going. Today I'm officially off blood pressure meds completely. With lifestyle changes, low sodium diet, low sugar, aerobic exercise and weight loss. I had blood pressure in the 170 to 180 systolic in January of 2025 after heart surgery on November 2024. I was 230 pounds and am current
I wanted to share with this group since I’ve gained so much value from this forum. Sometimes I think people don’t share their positive results enough, and it can really skew people’s ideas of what medicating hypertension will be like. I put off getting medicated for 15 years. My story was basically
I take 100 mg of Losartan daily, but before meds I was easily in the 140-150/90-100 range. Even after taking medication I was usually in the 130/90+ range. My resting heart rate used to sit at about 110 too. I felt like shit and my bod was so tense. But recently I stopped drinking and smoking and be
25M. When I was first diagnosed with hypertension (late 2022), I was hesitant to start any synthetic medication. I tried the “natural” route first — mainly beetroot juice. It did help a bit, but having to constantly buy, wash, cut, and juice beets was too time-consuming with my schedule as a univers
My blood pressure (seemingly) started giving me problems beginning of this year and I was put on losartan 50mg. I take that once a day and it seems to control my BP well (below 130/80). However, in the 4 months I've been on this medication, I've noticed when I'm on my period, my blood pressure shoot
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
AMLODIPINE is a ARB, while Losartan belongs to the ARB (Angiotensin II Receptor Blocker) class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles.
AMLODIPINE carries 4 FDA warnings. Losartan carries 1 FDA warning. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.