GEFITINIB vs IBRUTINIB

Hi Everyone, My father has been recently diagnosed with non-small cell lung cancer (NSCLC) and his NGS full panel report confirmed an EGFR Exon 19 deletion mutation(no ALK, ROS1, or other actionable markers) We were told that this mutation is eligible for targeted therapy, and our oncologist has pre

Hi everyone, I’m posting here because I’m feeling overwhelmed and could really use some perspective and hope from people who understand what we’re going through. My 70-year-old grandmother was recently diagnosed with Stage IV lung adenocarcinoma. Her PET-CT shows a large tumor (around 15 cm) in the

Hi everyone, I’m posting here because my family and I are looking for some guidance, real-life experiences, and a bit of hope during a difficult time. My 70-year-old grandmother was recently diagnosed with Stage IV lung adenocarcinoma. Her PET-CT showed a right lung mass with mild spread to the medi

I am brand new to CRISPR/Cas9 and would be very appreciative of input on my experimental plan/design! For context, I want to manipulate 4 cancer-associated genes - APC, TP53, SMAD4, and KRAS - in colonic organoid cells. I will transfect cells when they are in a single-cell suspension during passagin

My dad was recently diagnosed with a stage 4 Non-Small Cell Lung Cancer (NSCLC) with detected brain metastases (MRI), sub-type is adenocarcinoma. Through DNA extraction, it was found that he has mutations on EGFR exon 18-20. His treatment is moving fast and he's currently undergoing oral chemo with

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Company introduction Qianqiu Biological Technology Co., Limited Is a company mainly engaged in high quality pharmaceuticals, agricultural chemicals, pharmaceutical intermediates and other related products research and development and sales for the integration of high-tech enterprises. Analysis of te

Hey everyone, get ready for some deep due diligence, this time not for REGAL, but for SLS-009, buyout, and what the future will look like with buyout from a strategic acquirer. Before I start, I would suggest for those haven’t yet, read Part 1 and Part 2 that goes over the deep due diligence and mac

Hey everyone, get ready for some deep due diligence, this time not for REGAL, but for SLS-009, buyout, and what the future will look like with buyout from a strategic acquirer. Before I start, I would suggest for those haven’t yet, read Part 1 and Part 2 that goes over the deep due diligence and mac

Hi everyone. I’m looking for insight from others with CLL experience. My dad has CLL with 96% involvement in his bone marrow per recent biopsy. His platelets are low, and over the past two weeks his anemia has worsened very very quickly. Recent timeline: Hospitalized with hemoglobin \~7.5 and fever

To Those Who Wish to learn, I feel like I may be giving away a secret.... but... here it goes... Earlier today I had a [twitter conversation](https://twitter.com/sentivcapital/status/1663230898702106634) about AI in regards to potential for future impact on stocks. I received a lot of DMs and to be

I’ve been pretty successful in a media career but now, at 43, 3 years post my diagnosis with my cancer under control (no cure... a rare lymphoma/on ibrutinib forever) two kids 7 and 4 at home and the sole breadwinner for the family, I’m so disenchanted. I finally feel great health wise... back to m

I was researching to find out * Examples of cancer drugs in the past that came to market later where treatments already existed, but ended up being commercially successful - * What were the characteristics of these late entrants that led to their success and does Cosibelimab have some of these char

**Is progression a meaningful outcome measure for a patient with indolent lymphoma** **If I don't feel anything (i.e. asymptomatic) and can live for decades with my lymphoma should I even worry about the fact that I have some enlarged lymph nodes or abnormalities of my lab work ???** I had a dis

Apparently a patient had been administering the medication this way... It's on the ISMP do not crush list. I called the manufacturer (Pharmacyclics) and they had no data on administering through any enteral feeding tubes, so they recommended not to give the medication in this manner. I can't find an