Medical Disclaimer: This site provides informational comparisons only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or pharmacist before making medication decisions.
Compare GUANFACINE (Guanfacine) and LISDEXAMFETAMINE (Lisdexamfetamine Dimesylate) — clinical data, side effects, and patient experiences.
Guanfacine, Intuniv, Tenex · Non-Stimulant ADHD
How it works
12.1 Mechanism of Action Guanfacine is a central alpha 2A -adrenergic receptor agonist. Guanfacine is not a central nervous system (CNS) stimulant. The mechanism of action of guanf...
Approved for
Lisdexamfetamine Dimesylate, Vyvanse · CNS Stimulant
How it works
Other agent
Approved for
Estimated frequency (%) based on clinical trial data
Based on 30 Reddit discussions
GUANFACINE
47%
positive
15 threads
LISDEXAMFETAMINE
20%
positive
15 threads
% of discussions mentioning each side effect
15 Reddit threads analysed for GUANFACINE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
751 upvotes
Most discussed side effects in community
Having ADHD fucking sucks. It’s not quirky, fun, or something that needs to become an entire personality. I’ve seen so many TikTok accounts that are all just “here’s 5 reasons you have ADHD” and then they base everything they discuss as mundane nonsense that doesn’t even pertain to ADHD. “You migh
Let me tell you a story. I’m a dad with ADHD, my oldest son has ADHD inattentive type, the middle son has ADHD hyperactive type, the baby is a baby, but we already have a sense she’s got something going on already. In the mornings, I serve up morning meds for everyone. A vyvanse for dad, fluoxetine
My son is profoundly autistic and very minimally speaking with a host of comorbidities, including ADHD combined type. We tried several stimulant formulations. He couldn't sleep. He became aggressive. He has used clonidine + guanfacine before bed to sleep. Today he started his second dose of clonidi
Decided three years ago to pursue a PhD in a discipline I love after finally took my ADHD seriously. Pursuing a doctorate was something I just didn't think I could do because of how my brain handles unstructured tasks (like writing a dissertation). Turns out with the right drugs (guanfacine + wellbu
I haven’t been able to sit down and read literally just a CHAPTER of a book in like 6 years. I crave just…. Sitting down and focusing on one task. Reading a book. Doing a puzzle. Cleaning my room. For reference I am diagnosed with adhd-c and on Sertraline and Guanfacine. I been on both for like?
I can’t believe nobody has ever recommended this drug to me before. I always struggled with stimulants as there would be days where I would have breakdowns or hyper focus on the wrong thing, couldn’t sleep.. etc. I’ve been taking guanfacine and bupropion for about a month and I REALLY NOTICE a diffe
Maybe it’s just me but I’ve gone through a gauntlet of medications (Adderall, Focalin XR, Ritalin, Metadate, Vyvanse, Dexedrine, Concerta, Wellbutrin, Strattera, Guanfacine) and each time I’ve ended up disappointed in them. At best, they give me a bit of energy/wakefulness and make it slightly easie
This is really long. I’m tired and frustrated, sorry. So I just got off my 11p-7a in the emergency department. We have this one doc, LC, who I’m pretty sure is out to get me. Does this sound dramatic? Yes. Do I actually think it’s true? I’ve been trying to convince myself I’m crazy, but I actually
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
15 Reddit threads analysed for LISDEXAMFETAMINE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
1,011 upvotes
Most discussed side effects in community
In response to the ongoing shortage of ADHD medications, the U.S. Food and Drug Administration (FDA) has approved several generic versions of Vyvanse (lisdexamfetamine dimesylate) for the treatment of attention-deficit/hyperactivity disorder in people 6 years and older. Vyvanse is available in capsu
Just posted to the FDA's News section - [https://www.fda.gov/drugs/news-events-human-drugs/fda-approves-multiple-generics-adhd-and-bed-treatment](https://www.fda.gov/drugs/news-events-human-drugs/fda-approves-multiple-generics-adhd-and-bed-treatment) Excerpt: >FDA has approved several first gener
Last month, I paid around $200 for my Vyvanse, but this time when I picked up my meds, the copay was only $10. I don’t know if there was a mixup, if the company just drastically reduced their prices since the FDA approved generic versions, or something else, but I’m super happy. Edit: - I didn’t hi
I’m 28, and for almost as long as I can remember, I’ve been getting treated for PI ADHD. I have taken between 40-60 MG of Vyvanse/Lisdexamfetamine as a prescription to treat it since elementary school, but with this national shortage still going on, I’ve been struggling to get refills on time. I kn
https://en.wikipedia.org/wiki/Lisdexamfetamine#History "The expiration date for patent protection of lisdexamfetamine in the U.S. is February 24, 2023. Final approval and availability of generic versions of the medication in the U.S. is anticipated after this date" https://web.archive.org/web/202208
Purely anecdotal, but some possibly good news in this shitshow of a medication shortage. When I went in to pick up my Vyvanse, and they were out, the pharmacist told me, "I ordered generic Vyvanse to arrive tomorrow, but also wouldn't be surprised if it didn't make it with this delivery. Call in the
As many of you are aware by now, the current U.S. shortage of medications used to treat ADHD has patients and parents of patients who rely on these medications scrambling to fill their prescriptions, leaving some people in a position where they are starting a new medicine or going without. Discussio
I just moved to Illinois from Ohio and switched Medicaid services. For the past 2 years Ohio Medicaid has covered my 40 mg Vyvance prescription in full with essentially no issues. Today I went to fill my new prescription and was told that Illinois Medicaid won’t cover this because “I’m too old to t
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
GUANFACINE is a Non-Stimulant ADHD, while LISDEXAMFETAMINE belongs to the CNS Stimulant class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles.
GUANFACINE carries 4 FDA warnings. LISDEXAMFETAMINE carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.