BRIGATINIB vs NILOTINIB

Do you or your loved one have experience with Brigatinib (Alunbrig) for the first line treatment of ALK Positive NSCLC? Help Lung Cancer Canada provide insight by contacting us to share your experience and help lung cancer patients get access to this treatment. Email us at [email protected].

hey all 💗 it’s been a minute. my 16yo is in the sweet spot: highly concerning tumors have grown, but are not affecting function as of now. we’ve made the decision to start brigatinib in june, at the end of the school year. we have avastin on the back burner, trying to start with least “disruptive

My father, male, age 65, was diagnosed with Stage IV non-small cell lung cancer this past June. He has since undergone whole brain radiation and began taking the medication alectinib as his cancer contains an ALK mutation. After a couple of months, the alectinib caused terrible abdominal pain and hi

hi all ✨ sending everyone some love. also, long story short, my 15yo son has NF2, and has a slowly growing VS in the left; ss deaf from removal of fast-growing binuclear VS on the right. recent growth has sparked discussions of how to preserve his hearing. we have discussed avastin, and are also l

Just looking for some people who have been on either of these and their experiences! I started Dasatinib 100mg for my CML and it worked well for reducing my WBC and BCR-ABL. However, I was only on it for about 2 months as the side effects were pretty intolerable. Really severe bone pain, fatigue, he

Has anyone had any issues switching from brand to generic TKIs? Specifically Tasgina to Nilotinib. Counts have been good for a decade but now insurance making me change to Nilotinib. I know it’s basically the same med (just different fillers) but wanted to see if anyone had experience with it? Thank

Hi, the European Leukemia Net published its 2025 update of recommendations for the treatment of CML recently, you can find it on the internet ([2025 European LeukemiaNet recommendations for the management of chronic myeloid leukemia | Leukemia](https://www.nature.com/articles/s41375-025-02664-w)). T

Hey everyone, I’m 10 months into a chronic phase CML diagnosis with no detectable mutation. I started on Nilotinib, then moved to Dasatinib (up to 140mg), but my BCR’s been stuck around 20% and hasn’t dropped enough. Starting Ponatinib on Monday. If that doesn’t work, the plan is Asciminib, then tra

Hi guys, My husband has been living with CML for around 20 years now (age 36). He had been on Imatinib fot a long time, before he got changed on Nilotinib in 2020. Since he changed medication, his blood tests had always been stable (grade 4 or 4.5) until a few months ago, where he suddenly got to g

I'm about 6 months post diagnosis, and 4 months into TKIs (Tasigna 600mg daily). Super grateful to be TKI sensitive, with BCR-ABL1 down from 41% to .0066%, but now starting to process what life will be like living with CML and nilotinib. Fatigue and dry, itchy skin have been the main side effects so

Hello! Diagnosed with CML July 2024 and been taking Imatinib. However, for the past 6 months my CBC is not normal. My doctor decided to change tki to Nilotinib 600mg. Anyone who uses Nilotinib? It it better? My I know the side effects that you experience? Thank you 🙂

I’m 25 yo male diagnosed w cp cml in dec 2022. Responded well to nilotinib for 4 months with a hematologic relapse recently. Confirmed T315I mutation. Doc suggests ponatinib until we can schedule a bone marrow transplant. Anybody had similar experiences? What does my prognosis look like? Thanks for