ERDAFITINIB vs LORLATINIB

I have shared some details of my mom's experiences on erdafitinib in a clinical trial and wanted to share an amazing update -- she had about a 30% reduction in her tumor today (the image on the left) compared to February (the image on the right). This comes after another 20% reduction she had in ear

TLDR; summary of my BC experience through surgeries, gem/cis, Keytruda/Padcev, radiation, neuropathy that caused me to drop the therapy (cancer was stable), and potential next steps. Today I (43m) had my last dose of Keytruda. Back in April I had my last dose of Padcev. I see people here asking abou

Hi all! A few months back I posted about my mom (68) being put in a clinical trial with erdafitinib after her glioblastoma continued to progress following radiation and chemo after her brain surgery in February of this year. She was a candidate for this trial because of a fairly rare FGFR fusion her

US pharmer here. Hoping for assistance from any pharmacists that work in Canada. Have a patient with pancreatic cancer, oncology has recommended starting of Balversa (erdafitinib). Insurance of course is saying this is a no-go, as it is not currently FDA approved for pancreatic cancer. They are now

Hi all. My mom has recently been enrolled in a clinical trial testing the effectiveness of erdafitinib based off a fairly rare FGFR fusion her tumor has (about 3% of all cases of glioblastoma). She has just started taking the medication within the last week. This is after a 95%+ resection of her tum

Hey everyone, Long story short: I’m 27 and was recently diagnosed with stage 4 lung cancer ALK positive. It’s not curable, so I’ll be living with this for the rest of my life. I’m currently being treated at Memorial Sloan Kettering, and I’ll need to stay on a very specific (and very expensive) targe

HEADS UP THIS IS A LONG ONE!!! The past two years I’ve (27F) been dealing with severe breathing / wheezing problems. My PCP thought it was asthma, I was handed a pump and some montelukast. It continued and continued but I got used to it at a certain point and believed my doctor that it was just asth

Hello everyone, I’m writing as both a pulmonologist and a son. My mother has ALK-positive lung cancer, diagnosed in 2021. She has been on lorlatinib (Lorviqua) since March 2023, currently 50 mg daily, with an excellent and durable response, including complete response on recent scans. We are unfortu

I am a care partner for a 32 yr old Male who was just diagnosed with stage 4 NSCLC. Mets to liver, brain, bones (hip/spine) and lymph nodes. He got his ALK + diagnosis today and it was the first piece of ‘good news’ in weeks. His doctor has given him the option or Lorlatinib or a clinical study wher

A renowned oncologist specializing in targeted therapy and genetic treatment is now advising us to start **Lorlatinib** instead of **Lynparza** to treat my mom's (64F) pancreatic cancer with liver mets. Opposing what our current oncologist has advised us to do after we stopped chemo due to high bili

My dad has (60M) Stage IV NSCLC ALK+. Currently on Lorlatinib. It was effective for a bit but recent scans showed that the metastasized spots grew. Now, what are the alternative/ possible treatments to get it back under control? If anyone has any experience or thoughts, I would be very interested t