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Brand names: BALVERSA
12.1 Mechanism of Action Erdafitinib is a kinase inhibitor that binds to and inhibits enzymatic activity of FGFR1, FGFR2, FGFR3 and FGFR4 based on in vitro data. Erdafitinib inhibited FGFR phosphorylation and signaling and decreased cell viability in cell lines expressing FGFR genetic alterations, including point mutations, amplifications, and fusions. Erdafitinib demonstrated antitumor activity in FGFR-expressing cell lines and xenograft models derived from tumor types, including bladder cancer.
Contraindications
5 documented side effects by frequency
5 Reddit threads analysed for ERDAFITINIB
Overall Sentiment
Slightly negative
Comparison Threads
0
Avg Post Score
20 upvotes
Most discussed side effects in community
I have shared some details of my mom's experiences on erdafitinib in a clinical trial and wanted to share an amazing update -- she had about a 30% reduction in her tumor today (the image on the left) compared to February (the image on the right). This comes after another 20% reduction she had in ear
TLDR; summary of my BC experience through surgeries, gem/cis, Keytruda/Padcev, radiation, neuropathy that caused me to drop the therapy (cancer was stable), and potential next steps. Today I (43m) had my last dose of Keytruda. Back in April I had my last dose of Padcev. I see people here asking abou
Hi all! A few months back I posted about my mom (68) being put in a clinical trial with erdafitinib after her glioblastoma continued to progress following radiation and chemo after her brain surgery in February of this year. She was a candidate for this trial because of a fairly rare FGFR fusion her
US pharmer here. Hoping for assistance from any pharmacists that work in Canada. Have a patient with pancreatic cancer, oncology has recommended starting of Balversa (erdafitinib). Insurance of course is saying this is a no-go, as it is not currently FDA approved for pancreatic cancer. They are now
Hi all. My mom has recently been enrolled in a clinical trial testing the effectiveness of erdafitinib based off a fairly rare FGFR fusion her tumor has (about 3% of all cases of glioblastoma). She has just started taking the medication within the last week. This is after a 95%+ resection of her tum
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14 available comparisons
Dosage Forms
Tablet
Route
Oral