ERDAFITINIB vs GEFITINIB

I have shared some details of my mom's experiences on erdafitinib in a clinical trial and wanted to share an amazing update -- she had about a 30% reduction in her tumor today (the image on the left) compared to February (the image on the right). This comes after another 20% reduction she had in ear

TLDR; summary of my BC experience through surgeries, gem/cis, Keytruda/Padcev, radiation, neuropathy that caused me to drop the therapy (cancer was stable), and potential next steps. Today I (43m) had my last dose of Keytruda. Back in April I had my last dose of Padcev. I see people here asking abou

Hi all! A few months back I posted about my mom (68) being put in a clinical trial with erdafitinib after her glioblastoma continued to progress following radiation and chemo after her brain surgery in February of this year. She was a candidate for this trial because of a fairly rare FGFR fusion her

US pharmer here. Hoping for assistance from any pharmacists that work in Canada. Have a patient with pancreatic cancer, oncology has recommended starting of Balversa (erdafitinib). Insurance of course is saying this is a no-go, as it is not currently FDA approved for pancreatic cancer. They are now

Hi all. My mom has recently been enrolled in a clinical trial testing the effectiveness of erdafitinib based off a fairly rare FGFR fusion her tumor has (about 3% of all cases of glioblastoma). She has just started taking the medication within the last week. This is after a 95%+ resection of her tum

Hi Everyone, My father has been recently diagnosed with non-small cell lung cancer (NSCLC) and his NGS full panel report confirmed an EGFR Exon 19 deletion mutation(no ALK, ROS1, or other actionable markers) We were told that this mutation is eligible for targeted therapy, and our oncologist has pre

Hi everyone, I’m posting here because I’m feeling overwhelmed and could really use some perspective and hope from people who understand what we’re going through. My 70-year-old grandmother was recently diagnosed with Stage IV lung adenocarcinoma. Her PET-CT shows a large tumor (around 15 cm) in the

Hi everyone, I’m posting here because my family and I are looking for some guidance, real-life experiences, and a bit of hope during a difficult time. My 70-year-old grandmother was recently diagnosed with Stage IV lung adenocarcinoma. Her PET-CT showed a right lung mass with mild spread to the medi

I am brand new to CRISPR/Cas9 and would be very appreciative of input on my experimental plan/design! For context, I want to manipulate 4 cancer-associated genes - APC, TP53, SMAD4, and KRAS - in colonic organoid cells. I will transfect cells when they are in a single-cell suspension during passagin

My dad was recently diagnosed with a stage 4 Non-Small Cell Lung Cancer (NSCLC) with detected brain metastases (MRI), sub-type is adenocarcinoma. Through DNA extraction, it was found that he has mutations on EGFR exon 18-20. His treatment is moving fast and he's currently undergoing oral chemo with

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