CRIZOTINIB vs ERDAFITINIB

**Verified?** *(This bot cannot verify AMAs just yet)* **Date:** 2013-02-21 **[Link to submission](http://www.reddit.com/r/IAmA/comments/18ymad/)** (*Has self-text*) **[Link to my post](http://www.reddit.com/r/IAmA/comments/18ymad/tabledresser/c8jk1ce)** Questions|Answers :--|:-- [Would you rather m

Hello, My husband has ROS1-positive lung cancer with multiple brain metastases. He was treated with Crizotinib, but unfortunately the brain metastases have progressed. We are considering Lorlatinib as the next treatment option, but we have concerns about availability, cost, side effects, and the app

Hi all, I have posted here before a few times about my dad (64M). He was diagnosed with NSCLC adenocarcinoma stage 4 mets to hip on December 2024. He went through 6 rounds of chemo, tumors responded (shrunk a little but still active) and was disease was considered stable. Then he was put on maintena

Hey everyone, I hoped to pose a question. The UK NHS does not use MET amplification as a biomarker for mutation testing. My father, who has Stage 4 non-small cell lung cancer, was put on the conventional treatment regimen, chemo + immunotherapy (carboplatin-pemetrexed-pembrolizumab), because nothi

Hi, I have a rare stage-IV soft tissue sarcoma with mets to the lungs and lymph nodes. Does anyone on here have any experience with crizotinib (brand name in the USA is Xalkori)? I was taking another, similar MET inhibitor (cabozantinib/Cabometyx), but I'm switching due to progression while on cabom

Hello, My husband has ROS1-positive lung cancer with multiple brain metastases. He was treated with Crizotinib, but unfortunately the brain metastases have progressed. We are considering Lorlatinib as the next treatment option, but we have concerns about availability, cost, side effects, and the app

I have shared some details of my mom's experiences on erdafitinib in a clinical trial and wanted to share an amazing update -- she had about a 30% reduction in her tumor today (the image on the left) compared to February (the image on the right). This comes after another 20% reduction she had in ear

TLDR; summary of my BC experience through surgeries, gem/cis, Keytruda/Padcev, radiation, neuropathy that caused me to drop the therapy (cancer was stable), and potential next steps. Today I (43m) had my last dose of Keytruda. Back in April I had my last dose of Padcev. I see people here asking abou

Hi all! A few months back I posted about my mom (68) being put in a clinical trial with erdafitinib after her glioblastoma continued to progress following radiation and chemo after her brain surgery in February of this year. She was a candidate for this trial because of a fairly rare FGFR fusion her

US pharmer here. Hoping for assistance from any pharmacists that work in Canada. Have a patient with pancreatic cancer, oncology has recommended starting of Balversa (erdafitinib). Insurance of course is saying this is a no-go, as it is not currently FDA approved for pancreatic cancer. They are now

Hi all. My mom has recently been enrolled in a clinical trial testing the effectiveness of erdafitinib based off a fairly rare FGFR fusion her tumor has (about 3% of all cases of glioblastoma). She has just started taking the medication within the last week. This is after a 95%+ resection of her tum