Condition · MDD / GAD

Medications for depression & anxiety.

SSRIs and SNRIs are first-line, with bupropion and mirtazapine as alternatives. The two most-compared medications on DrugNote are Lexapro (escitalopram) and Zoloft (sertraline). Switching SSRIs is a common decision driven by sexual side-effects, activation, or weight changes.

§01 — Drug list

53 indexed medications.

Grouped here by therapeutic class. Click any drug for FDA label data, side-effect frequency, and patient experiences.

Tricyclic Antidepressant
AMITRIPTYLINE HCL
Brand: Amitriptyline HCL
Tricyclic Antidepressant
AMITRIPTYLINE HYDROCHLORIDE
Brand: Amitriptyline Hydrochloride
Atypical Antidepressant (NDRI)
BUPROPION
Brand: bupropion
Atypical Antidepressant (NDRI)
BUPROPION HCL ER
Brand: Bupropion HCL ER (XL)
Atypical Antidepressant (NDRI)
BUPROPION HYDROCHLORIDE
Brand: buPropion Hydrochloride XL
SSRI
CITALOPRAM
Brand: Citalopram
SSRI
CITALOPRAM HYDROBROMIDE
Brand: Citalopram
Tricyclic Antidepressant
CLOMIPRAMINE HYDROCHLORIDE
Brand: CLOMIPRAMINE HYDROCHLORIDE
Tricyclic Antidepressant
Desipramine
Brand: Norpramin
SNRI
DESVENLAFAXINE
Brand: Desvenlafaxine
SNRI
DESVENLAFAXINE ER
Brand: Desvenlafaxine ER
SNRI
DESVENLAFAXINE SUCCINATE
Brand: Pristiq Extended-Release
Tricyclic Antidepressant
DOXEPIN
Brand: Doxepin
Tricyclic Antidepressant
DOXEPIN HCL
Brand: Doxepin HCL
Tricyclic Antidepressant
DOXEPIN HYDROCHLORIDE
Brand: Doxepin hydrochloride
SNRI
DULOXETINE
Brand: DULOXETINE HYDROCHLORIDE
SNRI
DULOXETINE D
Brand: Duloxetine D/R
SNRI
DULOXETINE HYDROCHLORIDE
Brand: Duloxetine Delayed-Release
SSRI (Selective Serotonin Reuptake Inhibitor)
Escitalopram
Brand: Lexapro
SSRI
ESCITALOPRAM ORAL
Brand: Escitalopram Oral Solution
SSRI
ESCITALOPRAM OXALATE
Brand: Escitalopram
SSRI
FLUOXETINE
Brand: Fluoxetine
SSRI
FLUOXETINE HCL
Brand: Fluoxetine HCL
SSRI
FLUOXETINE HYDROCHLORIDE
Brand: Fluoxetine
SSRI
FLUVOXAMINE MALEATE
Brand: Fluvoxamine Maleate
Tricyclic Antidepressant
Imipramine
Brand: Tofranil
Tricyclic Antidepressant
IMIPRAMINE HYDROCHLORIDE
Brand: Imipramine Hydrochloride
SNRI
Levomilnacipran
Brand: Fetzima
SNRI
Milnacipran
Brand: Savella
SNRI
MILNACIPRAN HYDROCHLORIDE
Brand: Savella
Atypical Antidepressant
MIRTAZAPINE
Brand: Mirtazapine
Atypical Antidepressant (NDRI)
NALTREXONE HYDROCHLORIDE AND BUPROPION HYDROCHLORIDE
Atypical Antidepressant
Nefazodone
Brand: Serzone
Atypical Antidepressant
NEFAZODONE HYDROCHLORIDE
Brand: Nefazodone Hydrochloride
Tricyclic Antidepressant
NORTRIPTYLINE HCL
Brand: Nortriptyline HCL
Tricyclic Antidepressant
NORTRIPTYLINE HYDROCHLORIDE
Brand: NORTRIPTYLINE HYDROCHLORIDE
SSRI
PAROXETINE
Brand: Paroxetine
SSRI
PAROXETINE HYDROCHLORIDE
Brand: PAROXETINE
SSRI
PAROXETINE HYDROCHLORIDE HEMIHYDRATE
Brand: Paroxetine
MAOI
Phenelzine
Brand: Nardil
SSRI (Selective Serotonin Reuptake Inhibitor)
Sertraline
Brand: Zoloft
SSRI
SERTRALINE HCL
Brand: Sertraline HCL
SSRI
SERTRALINE HYDROCHLORIDE
Brand: Sertraline Hydrochloride
MAOI
TRANYLCYPROMINE
Brand: Tranylcypromine
Atypical Antidepressant
TRAZODONE HCL
Brand: Trazodone HCL
Atypical Antidepressant
TRAZODONE HYDROCHLORIDE
Brand: Trazodone Hydrochloride
Atypical Antidepressant
TRAZODONE HYDROCHLORIDE ORAL
Brand: RALDESY TM
Tricyclic Antidepressant
TRIMIPRAMINE
Brand: Trimipramine
Tricyclic Antidepressant
TRIMIPRAMINE MALEATE
Brand: Trimipramine Maleate
SNRI
VENLAFAXINE
Brand: Venlafaxine
SNRI
VENLAFAXINE HYDROCHLORIDE
Brand: Venlafaxine Hydrochloride
Atypical Antidepressant
VILAZODONE HYDROCHLORIDE
Brand: VILAZODONE HYDROCHLORIDE
Atypical Antidepressant
VORTIOXETINE
Brand: Trintellix

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